New drug targets genetic weakness in Tough-to-Treat lung cancer

NCT ID NCT06593522

Recruiting now Disease control Sponsor: Amgen Source: ClinicalTrials.gov ↗

Summary

This study is testing an experimental drug called AMG 193 for people with advanced non-small cell lung cancer that has a specific genetic change called MTAP-deletion and has stopped responding to prior treatments. The main goals are to see if the drug is safe, if it shrinks tumors, and how the body processes it. The study will enroll about 200 participants and is currently recruiting.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Adana Sehir Egitim ve Arastirma Hastanesi
RECRUITING

Adana, 01370, Turkey (Türkiye)
Aichi Cancer Center
RECRUITING

Nagoya, Aichi-ken, 464-8681, Japan
Ajou University Hospital
RECRUITING

Suwon-si Gyeonggi-do, 16499, South Korea
Ankara Bilkent Sehir Hastanesi
RECRUITING

Ankara, 06800, Turkey (Türkiye)
Bagcilar Medipol Mega Universite Hastanesi
RECRUITING

Istanbul, 34214, Turkey (Türkiye)
Beijing Cancer Hospital
RECRUITING

Beijing, Beijing Municipality, 100142, China
Beijing Cancer Hospital
RECRUITING

Beijing, 100142, China
Beijing Chest Hospital, Capital Medical University
RECRUITING

Beijing, 101149, China
Calvary Mater Newcastle Hospital
RECRUITING

Waratah, New South Wales, 2298, Australia
Cancer Research South Australia
RECRUITING

Adelaide, South Australia, 5000, Australia
Cancer and Hematology Centers of Western Michigan
RECRUITING

Grand Rapids, Michigan, 49503, United States
Cedars-Sinai Medical Center
RECRUITING

Los Angeles, California, 90048, United States
Centro Paulista de Oncologia
RECRUITING

São Paulo, 04538-132, Brazil
Cha Bundang Medical Center, Cha University
RECRUITING

Seongnam-si, Gyeonggi-do, 13496, South Korea
City of Hope National Medical Center
RECRUITING

Duarte, California, 91010, United States
City of Hope Orange County Lennar Foundation Cancer Center
RECRUITING

Duarte, California, 91010, United States
Cross Cancer Institute
RECRUITING

Edmonton, Alberta, T6G 1Z2, Canada
Eastern Connecticut Hematology and Oncology Associates
RECRUITING

Norwich, Connecticut, 06360, United States
Erasmus Medisch Centrum
RECRUITING

Rotterdam, 3015 GD, Netherlands
Fakultni Thomayerova nemocnice
RECRUITING

Prague, 140 59, Czechia
Fakultni nemocnice Olomouc
RECRUITING

Olomouc, 779 00, Czechia
Fund Faculdade Regional Med Sao Jose Rio Preto
RECRUITING

São José do Rio Preto, São Paulo, 15090-000, Brazil
Fundacao Antonio Prudente - Hosp AC Camargo
RECRUITING

São Paulo, São Paulo, 01509-900, Brazil
Fundacao Champalimaud
RECRUITING

Lisbon, 1400-038, Portugal
Fundacao pio xII Barretos
RECRUITING

Barretos, São Paulo, 14784-400, Brazil
Gazi Universitesi Saglik Arastirma ve Uygulama Merkezi Gazi Hastanesi
RECRUITING

Ankara, 06560, Turkey (Türkiye)
GenesisCare -North Shore Oncology
RECRUITING

St Leonards, New South Wales, 2065, Australia
Hartford HealthCare Cancer Institute - Manchester
RECRUITING

Plainville, Connecticut, 06062, United States
Henan Cancer Hospital
RECRUITING

Zhengzhou, Henan, 450001, China
Hopitaux Universitaires de Geneve
RECRUITING

Geneva, 1211, Switzerland
Hospital Cuf porto
RECRUITING

Porto, 4100-180, Portugal
Hospital Nossa Senhora da Conceicao
RECRUITING

Porto Alegre, Rio Grande do Sul, 91010-004, Brazil
Hospital Sao Lucas da Pontificia Universidade Catolica do Rio Grande do Sul
RECRUITING

Porto Alegre, Rio Grande do Sul, 90610-000, Brazil
Instituto Portugues de Oncologia do Porto Francisco Gentil, EPE
RECRUITING

Porto, 4200-072, Portugal
Instituto de Educacao Pesquisa e Gestao em Saude
RECRUITING

Rio de Janeiro, 22775-001, Brazil
Instituto do Cancer Estado SP Icesp
RECRUITING

São Paulo, São Paulo, 01246-000, Brazil
Jilin Cancer Hospital
RECRUITING

Changchun, Jilin, 130012, China
Jinan Central Hospital
RECRUITING

Jinan, Shandong, 250013, China
Kantonsspital Sankt Gallen
RECRUITING

Sankt Gallen, 9007, Switzerland
Liga Norte-Riograndense Contra O Cancer
RECRUITING

Natal, Rio Grande do Norte, 59062-000, Brazil
London Health Sciences Centre
RECRUITING

London, Ontario, N6A 4L6, Canada
Masarykuv onkologicky ustav
RECRUITING

Brno, 656 53, Czechia
Mater Hospital Brisbane
RECRUITING

South Brisbane, Queensland, 4101, Australia
McGill University Health Centre Glen Site
RECRUITING

Montreal, Quebec, H4A 3J1, Canada
Medstar Georgetown University Hospital
RECRUITING

Washington D.C., District of Columbia, 20007, United States
Memorial Bahcelievler Hastanesi
RECRUITING

Istanbul, 34180, Turkey (Türkiye)
Mengchao Hepatobiliary Hospital of Fujian Medical University
RECRUITING

Fuzhou, Fujian, 350028, China
National Cancer Center Hospital
RECRUITING

Chuo-ku, Tokyo, 104-0045, Japan
National Cancer Center Hospital East
RECRUITING

Kashiwa-shi, Chiba, 277-8577, Japan
National Cancer Centre Singapore
RECRUITING

Singapore, 168583, Singapore
National Cheng Kung University Hospital
RECRUITING

Tainan, 70403, Taiwan
National Taiwan University Hospital
RECRUITING

Taipei, 10002, Taiwan
National University Hospital
RECRUITING

Singapore, 119074, Singapore
Nederlands Kanker Instituut Antoni van Leeuwenhoekziekenhuis
RECRUITING

Amsterdam, 1066 CX, Netherlands
Núcleo de Oncologia da Bahia
RECRUITING

Salvador, Estado de Bahia, 40170-110, Brazil
Our Lady of the Lake Cancer Institute
RECRUITING

Baton Rouge, Louisiana, 70808, United States
Pauls Stradins Clinical University Hospital
RECRUITING

Riga, 1002, Latvia
Prince of Wales Hospital, Chinese University of Hong Kong
RECRUITING

Shatin, New Territories, Hong Kong
Princess Margaret Cancer Centre
RECRUITING

Toronto, Ontario, M5G 2M9, Canada
Queen Mary Hospital, The University of Hong Kong
RECRUITING

Hong Kong, Hong Kong
Riga East Clinical University Hospital
RECRUITING

Riga, 1079, Latvia
Rocky Mountain Cancer Centers
RECRUITING

Denver, Colorado, 80218, United States
Sarah Cannon Research Institute
RECRUITING

Dallas, Texas, 75230, United States
Sarah Cannon Research Institute Oncology Partners
RECRUITING

Nashville, Tennessee, 37203, United States
Severance Hospital Yonsei University Health System
RECRUITING

Seoul, 03722, South Korea
Shanghai East Hospital
RECRUITING

Shanghai, Shanghai Municipality, 200123, China
Shizuoka Cancer Center
RECRUITING

Sunto-gun, Shizuoka, 411-8777, Japan
Sint Jansdal Ziekenhuis
RECRUITING

Harderwijk, 3844 DG, Netherlands
Taichung Veterans General Hospital
RECRUITING

Taichung, 40705, Taiwan
Texas Oncology - Dallas Fort Worth
RECRUITING

Dallas, Texas, 75246, United States
Texas Oncology Central/South Texas
RECRUITING

Austin, Texas, 78745, United States
Texas Oncology Northeast Texas
RECRUITING

Tyler, Texas, 75702, United States
The Cancer Institute Hospital of Japanese Foundation for Cancer Research
RECRUITING

Koto-ku, Tokyo, 135-8550, Japan
The Catholic University of Korea St Vincents Hospital
RECRUITING

Suwon-si, Gyeonggi-do, 16247, South Korea
The First Affiliated Hospital Zhejiang University School Of Medicine
RECRUITING

Hangzhou, Zhejiang, 310003, China
The First Affiliated Hospital of Zhengzhou University
RECRUITING

Zhengzhou, Henan, 450052, China
The Second Xiangya Hospital of Central South University
RECRUITING

Changsha, Hunan, 410011, China
Trinity Health Saint Joseph Mercy Ann Arbor
RECRUITING

Ann Arbor, Michigan, 48106, United States
US Oncology Research Investigational Products Center
RECRUITING

Irving, Texas, 75063, United States
Unidade Local de Saude de Braga, EPE
RECRUITING

Braga, 4710-243, Portugal
Union Hospital Tongji Medical College Huazhong University of Science and Technology
RECRUITING

Wuhan, Hubei, 430022, China
United States Oncology Regulatory Affairs Corporate Office
RECRUITING

Nashville, Tennessee, 37203, United States
Universitaetsspital Basel
RECRUITING

Basel, 4031, Switzerland
University of California Los Angeles
RECRUITING

Los Angeles, California, 90095, United States
Valkyrie Clinical Trials
RECRUITING

Los Angeles, California, 90067, United States
Virginia Cancer Specialists PC
RECRUITING

Fairfax, Virginia, 22031, United States
Vseobecna fakultni nemocnice v Praze
RECRUITING

Prague, 128 08, Czechia
Wakayama Medical University Hospital
RECRUITING

Wakayama, Wakayama, 641-8510, Japan
West China Hospital Sichuan University
RECRUITING

Chengdu, Sichuan, 610041, China
William Osler Health System - Brampton Civic Hospital
RECRUITING

Brampton, Ontario, L6R 3J7, Canada
Zhejiang Cancer Hospital
RECRUITING

Hangzhou, Zhejiang, 310005, China

Conditions

Explore the condition pages connected to this study.

MTAP-DELETED NSCLC