New drug trial targets genetic weakness in Tough-to-Treat lung cancers

NCT ID NCT06333951

Recruiting now Disease control Sponsor: Amgen Source: ClinicalTrials.gov ↗

Summary

This study is testing a new drug, AMG 193, alone and in combination with other cancer therapies for adults with advanced lung or chest tumors that have a specific genetic change called MTAP-deletion. The main goals are to find the safest and most effective dose and to see how well the body handles the drug. It will involve about 500 participants to check for side effects and see if the treatment helps control the cancer.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Adana Sehir Egitim ve Arastirma Hastanesi
RECRUITING

Adana, 01370, Turkey (Türkiye)
Aichi Cancer Center
RECRUITING

Nagoya, Aichi-ken, 464-8681, Japan
Alexandra Hospital
RECRUITING

Athens, 11528, Greece
Ankara Bilkent Sehir Hastanesi
RECRUITING

Ankara, 06800, Turkey (Türkiye)
Asan Medical Center
RECRUITING

Seoul, 05505, South Korea
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
RECRUITING

Milan, 20162, Italy
Beijing Cancer Hospital
RECRUITING

Beijing, 100142, China
Beneficencia Portuguesa de Sao Paulo - Bp
RECRUITING

São Paulo, São Paulo, 01509-900, Brazil
Cemic
RECRUITING

Ciudad Autonoma Buenos Aires, C1431FWO, Argentina
Centre Hospitalier Universitaire de Liege - Sart Tilman
RECRUITING

Liège, 4000, Belgium
Centro Ricerche Cliniche Di Verona Societa responsabilita limitata
RECRUITING

Verona, 37126, Italy
Centrum Medyczne Hope Clinic Sebastian Szklener
RECRUITING

Lublin, 20-701, Poland
Cipo - Centro Integrado de Pesquisa em Oncologia
RECRUITING

Porto Alegre, Rio Grande do Sul, 91350-200, Brazil
City of Hope National Medical Center
TERMINATED

Duarte, California, 91010, United States
City of Hope Orange County Lennar Foundation Cancer Center
RECRUITING

Duarte, California, 91010, United States
Comprehensive Blood and Cancer Center
RECRUITING

Bakersfield, California, 93309, United States
Comprehensive Cancer Centers of Nevada
TERMINATED

Las Vegas, Nevada, 89169, United States
Eastern Connecticut Hematology and Oncology Associates
TERMINATED

Norwich, Connecticut, 06360, United States
European Interbalkan Medical Center
RECRUITING

Thessaloniki, 55236, Greece
Fondazione IRCCS Istituto Nazionale dei Tumori
RECRUITING

Alessandria, 15100, Italy
Fox Chase Cancer Center
RECRUITING

Philadelphia, Pennsylvania, 19111, United States
Fund Faculdade Regional Med Sao Jose Rio Preto
RECRUITING

São José do Rio Preto, São Paulo, 15090-000, Brazil
Futuremeds spolka z ograniczona odpowiedzialnoscia
RECRUITING

Krakow, 31-501, Poland
General Hospital Of Thessaloniki Papageorgiou
RECRUITING

Thessaloniki, 56429, Greece
Guangdong Provincial Peoples Hospital
RECRUITING

Guangzhou, Guangdong, 510000, China
Gustave Roussy
RECRUITING

Villejuif, 94805, France
Hacettepe Universitesi Tip Fakultesi Hastanesi
RECRUITING

Ankara, 06230, Turkey (Türkiye)
HealthPartners Institute
RECRUITING

Saint Paul, Minnesota, 55102, United States
Hightower Clinical
RECRUITING

Oklahoma City, Oklahoma, 73102, United States
Hopital de la Timone
RECRUITING

Marseille, 13005, France
Hospital Clinic i Provincial de Barcelona
RECRUITING

Barcelona, Catalonia, 08036, Spain
Hospital Universitari Vall d Hebron
RECRUITING

Barcelona, Catalonia, 08035, Spain
Hospital Universitario 12 de Octubre
RECRUITING

Madrid, 28041, Spain
Hospital Universitario Austral
RECRUITING

Pilar, Buenos Aires, B1629ODT, Argentina
IRCCS Istituto Clinico Humanitas
RECRUITING

Rozzano (MI), 20089, Italy
Institut Bergonie
RECRUITING

Bordeaux, 33000, France
Institut de Cancerologie de l Ouest Rene Gauducheau
RECRUITING

Saint-Herblain, 44805, France
Instituto Argentino de Diagnóstico y Tratamiento
RECRUITING

Ciudad Automona de Buenos Aires, Buenos Aires, C1117ABC, Argentina
Instituto Cancer Sao Paulo Icesp
RECRUITING

São Paulo, 01246-000, Brazil
Instytut Centrum Zdrowia Matki Polki
RECRUITING

Lodz, 93-338, Poland
Jilin Cancer Hospital
RECRUITING

Changchun, Jilin, 130012, China
Medizinische Universitaet Graz
RECRUITING

Graz, 8036, Austria
Medizinische Universitaet Innsbruck
RECRUITING

Innsbruck, 6020, Austria
Mengchao Hepatobiliary Hospital of Fujian Medical University
RECRUITING

Fuzhou, Fujian, 350028, China
Narodowy Instytut Onkologii im Marii Sklodowskiej-Curie Panstwowy Instytut Badawczy
RECRUITING

Gliwice, 44-102, Poland
National Cancer Center Hospital East
RECRUITING

Kashiwa-shi, Chiba, 277-8577, Japan
National Cheng Kung University Hospital
RECRUITING

Tainan, 70403, Taiwan
New York University Grossman School of Medicine
RECRUITING

New York, New York, 10016, United States
Northwest Medical Specialties, PLLC
RECRUITING

Tacoma, Washington, 98405, United States
Oncology Consultants Cancer Center
TERMINATED

Houston, Texas, 77030, United States
Oncosite Centro de Pesquisa Clinica Em Oncologia Ltda
RECRUITING

Ijuí, Rio Grande do Sul, 98700-000, Brazil
Orange Health Service
RECRUITING

Orange, New South Wales, 2800, Australia
Perlmutter Cancer Center at New York University Langone Hospital----Long Island
RECRUITING

New York, New York, 10016, United States
Prince of Wales Hospital, Chinese University of Hong Kong
RECRUITING

Shatin, New Territories, Hong Kong
Princess Margaret Cancer Centre
RECRUITING

Toronto, Ontario, M5G 2M9, Canada
Queen Mary Hospital, The University of Hong Kong
RECRUITING

Hong Kong, Hong Kong
Radboud Universitair Medisch Centrum
RECRUITING

Nijmegen, 6525 GA, Netherlands
Rocky Mountain Cancer Centers
RECRUITING

Denver, Colorado, 80218, United States
Roswell Park Cancer Institute
RECRUITING

Buffalo, New York, 32224, United States
Saint Lukes Hospital of Kansas City
TERMINATED

Kansas City, Missouri, 64111, United States
Seoul National University Hospital
RECRUITING

Seoul, 03080, South Korea
Shizuoka Cancer Center
RECRUITING

Sunto-gun, Shizuoka, 411-8777, Japan
Taipei Veterans General Hospital
RECRUITING

Taipei, 11217, Taiwan
Texas Oncology - Dallas Fort Worth
RECRUITING

Dallas, Texas, 75246, United States
Texas Oncology Northeast Texas
RECRUITING

Tyler, Texas, 75702, United States
The First Affiliated Hospital of Zhengzhou University
RECRUITING

Zhengzhou, Henan, 450052, China
The Queen Elizabeth Hospital
RECRUITING

Woodville South, South Australia, 5011, Australia
Translational Research in Oncology US Inc, Trio Central Pharmacy
RECRUITING

Los Angeles, California, 90095, United States
US Oncology Research Investigational Products Center
RECRUITING

Dallas, Texas, 75246, United States
Union Hospital Tongji Medical College Huazhong University of Science and Technology
RECRUITING

Wuhan, Hubei, 430022, China
United States Oncology Regulatory Affairs Corporate Office
RECRUITING

Nashville, Tennessee, 37203, United States
Universitaetsklinikum Essen
RECRUITING

Essen, 45147, Germany
Universitaetsklinikum Heidelberg
RECRUITING

Heidelberg, 69126, Germany
Universitaetsklinikum Wuerzburg
RECRUITING

Würzburg, 97078, Germany
University of California Irvine
RECRUITING

Orange, California, 92868-3217, United States
University of California Los Angeles
RECRUITING

Santa Monica, California, 90404, United States
University of Pittsburgh Medical Center
RECRUITING

Pittsburgh, Pennsylvania, 15232, United States
University of Tennessee Medical Center Knoxville
RECRUITING

Knoxville, Tennessee, 37920, United States
Uniwersyteckie Centrum Kliniczne
RECRUITING

Gdansk, 80-214, Poland
Upstate University Hospital
RECRUITING

Syracuse, New York, 13210, United States
Virginia Cancer Specialists PC
RECRUITING

Fairfax, Virginia, 22031, United States
Wakayama Medical University Hospital
RECRUITING

Wakayama, Wakayama, 641-8510, Japan
West China Hospital Sichuan University
RECRUITING

Chengdu, Sichuan, 610041, China

Conditions

Explore the condition pages connected to this study.

NON SMALL CELL LUNG CANCER THORACIC TUMORS