New vaccine trial targets Alzheimer's in High-Risk groups

NCT ID NCT05462106

Summary

This study is testing an investigational vaccine called ACI-24.060 to see if it is safe and can help the body's immune system fight the harmful amyloid proteins linked to Alzheimer's disease. It is enrolling 176 adults who either have very early-stage Alzheimer's (prodromal) or are adults with Down syndrome who are at high risk for developing Alzheimer's. The main goals are to check for side effects and see if the vaccine triggers an immune response that reduces amyloid in the brain.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Barrow Neurological Institute

    RECRUITING

    Phoenix, Arizona, 85013, United States

  • Cambridge and Peterborough NHS Foundation Trust - Windsor Research Units

    RECRUITING

    Cambridge, United Kingdom

  • Fundació ACE, Institut Català de Neurociències Aplicades

    RECRUITING

    Barcelona, Spain

  • Hospital Clínico San Carlos

    RECRUITING

    Madrid, Spain

  • Hospital Universitario Marqués de Valdecilla

    RECRUITING

    Santander, Spain

  • Hospital Universitario Virgen De Las Nieves

    WITHDRAWN

    Granada, Spain

  • Hospital Universitario de la Princesa

    RECRUITING

    Madrid, Spain

  • Hospital Universitario y Politécnico La Fe

    RECRUITING

    Valencia, Spain

  • Hospital de la Santa Creu i Sant Pau

    RECRUITING

    Barcelona, Spain

  • Indiana University / IU Health

    RECRUITING

    Indianapolis, Indiana, 46202, United States

  • Liverpool University Hospitals NHS Foundation Trust

    RECRUITING

    Liverpool, United Kingdom

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

  • Oxford Health NHS Foundation Trust

    RECRUITING

    Oxford, United Kingdom

  • Re:Cognition Health Limited

    RECRUITING

    London, United Kingdom

  • South London and Maudsley NHS Foundation Trust of The Maudsley Hospital

    RECRUITING

    London, United Kingdom

  • The Washington University

    RECRUITING

    St Louis, Missouri, 63130, United States

  • UT Health San Antonio

    RECRUITING

    San Antonio, Texas, 78229, United States

  • University of Kansas Medical Center Research Institute

    RECRUITING

    Fairway, Kansas, 66205-2513, United States

  • Vanderbilt University Medical Center

    RECRUITING

    Nashville, Tennessee, 37232-2103, United States

Conditions

Explore the condition pages connected to this study.