Ultrasound may help Alzheimer's drugs reach the brain

NCT ID NCT05469009

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 27 times

Summary

This study tests whether using focused ultrasound to temporarily open the blood-brain barrier is safe and feasible when combined with standard antibody therapy for people with mild Alzheimer's disease or mild cognitive impairment. The approach aims to help more medication reach the brain. Fifteen participants will be monitored for side effects and changes in brain plaques and cognitive function.

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Contacts and locations

Locations

  • West Virginia University Rockefeller Neuroscience Institute

    Morgantown, West Virginia, 26506, United States

Conditions

Explore the condition pages connected to this study.