New PET dye could spot Alzheimer's early in the brain

NCT ID NCT07422857

Recruiting now Diagnosis Sponsor: JYAMS PET Research & Development Limited Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new injection called [18F]-APN-1607 that helps a PET scan see harmful tau tangles in the brain, which are linked to Alzheimer's disease. About 316 adults aged 50 and older with normal memory, mild memory problems, or Alzheimer's dementia will get the injection and a brain scan. The goal is to see how well the scan can tell who has Alzheimer's-related changes, which could lead to earlier and more accurate diagnosis.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease dementia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SUBJECTS WITH MILD COGNITIVE IMPAIRMENT (MCI) OF AD, ALZHEIMER'S DISEASE (AD) DEMENTIA

Contacts and locations

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Locations

Huashan Hospital of Fudan University
RECRUITING

Shanghai, Province, 201199, China

Contact Phone: •••-•••-•••• Email: •••••@•••••
Union Hospital Tongji Medical College Huazhong University of Science and Technology
NOT_YET_RECRUITING

Wuhan, Hubei, 430000, China