Major trial tests new pill to slow Alzheimer's decline

NCT ID NCT03446001

Summary

This study tested whether a daily pill called TRx0237 could safely slow the progression of Alzheimer's disease. It involved 598 people with mild to moderate Alzheimer's who took either the drug or a placebo for one year. The main goals were to see if the drug could help people maintain their thinking skills and ability to perform daily activities better than those taking the placebo.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • ATP Clinical Research, Inc.

    Costa Mesa, California, 92626, United States

  • Advance Medical Research Center

    Miami, Florida, 33135, United States

  • Advanced Memory Research of NJ PC

    Toms River, New Jersey, 08755, United States

  • Albany Medical College

    Albany, New York, 12208, United States

  • Allied Biomedical Research Institute

    Miami, Florida, 33155, United States

  • Alpha Recherche Clinique

    Québec, G3K 2P8, Canada

  • Alzheimer's Memory Center

    Charlotte, North Carolina, 28270, United States

  • Alzheimer's Research and Treatment Center

    Wellington, Florida, 33414, United States

  • Arizona Research Center

    Phoenix, Arizona, 85053, United States

  • Atria Clinical Research

    Little Rock, Arkansas, 72209, United States

  • Azienda Ospedaliera San Gerardo - Clinica Neurologica

    Monza, 20900, Italy

  • Azienda Ospedaliera Sant'Andrea

    Roma, 00189, Italy

  • Bioclinica Research

    Orlando, Florida, 32806, United States

  • Biomed Research Institute, Inc

    Miami, Florida, 33126, United States

  • CBRI - Roper Hospital

    Charleston, South Carolina, 29414, United States

  • CCM Clinical Research Group

    Miami, Florida, 33133, United States

  • CHU Bordeaux - Pellegrin

    Bordeaux, 33076, France

  • CHU de Limoges

    Limoges, 87042, France

  • CHU de Rennes

    Rennes, 35009, France

  • CRC Gerontopole Cite de la Sante, Hôpital La Grave

    Toulouse, 31059, France

  • California Neuroscience Medical Group

    Sherman Oaks, California, 91403, United States

  • Centro de salud de San Juan, Unidad de Investigación Neurociencias

    Salamanca, 37005, Spain

  • Centrum Medyczne NEUROMED

    Bydgoszcz, 85-163, Poland

  • Centrum Medyczne NeuroProtect

    Warsaw, 01-684, Poland

  • Clinica Neurologica Santa Maria della Misericordia

    Udine, 33100, Italy

  • Clinique Mémoire de l'Outaouais

    Gatineau, Quebec, J8T 8J1, Canada

  • Cliniques Universitaires Saint-Luc

    Brussels, 1200, Belgium

  • Coastal Neurology

    Port Royal, South Carolina, 29935, United States

  • Emerald Coast Center for Neurological Disorders

    Pensacola, Florida, 32504, United States

  • Euromedis Sp. z o.o.

    Szczecin, 70-111, Poland

  • Excell Research, Inc.

    Oceanside, California, 92056, United States

  • Finlay Medical Research

    Greenacres City, Florida, 33467, United States

  • Finlay Medical Research

    Miami, Florida, 33126, United States

  • Florida International Research Center

    Miami, Florida, 33173, United States

  • Foundation Institute G.Giglio

    Cefalù, 90015, Italy

  • Fullerton Neurology and Headache Center

    Fullerton, California, 92835, United States

  • Future Care Solution, LLC

    Miami, Florida, 33165, United States

  • Georgia Neurology and Sleep Medicine Associates

    Suwanee, Georgia, 30024, United States

  • Glasgow Memory Clinic Ltd

    Glasgow, G20 0XA, United Kingdom

  • Guidechauliac Hospital

    Montpellier, 34295, France

  • HB Clinical Trials Inc.

    Fountain Valley, California, 92708, United States

  • Health Care Family Rehab and Research

    Miami, Florida, 33015, United States

  • Hoag Memorial Hospital Presbyterian

    Newport Beach, California, 92663, United States

  • Hopital des Charpennes

    Villeurbanne, 69100, France

  • Hospital General de Catalunya

    Barcelona, 08195, Spain

  • Hospital Universitario 12 de Octubre

    Madrid, 28041, Spain

  • Hospital Universitario Doctor Peset

    Valencia, 46017, Spain

  • Hospital Universitario Mutua Terrassa

    Terrassa, 08222, Spain

  • Hospital Universitario QuironSalud Madrid

    Madrid, 28223, Spain

  • Hospital Virgen de la Macarena

    Seville, 41009, Spain

  • Hospitales de Madrid

    Madrid, 28015, Spain

  • Hôpital Laënnec - CHU de Nantes

    Nantes, 44093, France

  • Hôpital Neurologique Pierre Wertheimer

    Bron, 69677, France

  • IMIC Inc

    Palmetto Bay, Florida, 33157, United States

  • IPS Research Company

    Oklahoma City, Oklahoma, 73106, United States

  • IRCCS Centro S. Giovanni di Dio Fatebenefratelli

    Brescia, 25125, Italy

  • IRCCS Fondazione Santa Lucia

    Rome, 00179, Italy

  • Imaging Endpoints Research

    Scottsdale, Arizona, 85258, United States

  • Indago Research & Health Center, Inc.

    Hialeah, Florida, 33012, United States

  • Indywidualna Praktyka Lekarska

    Lublin, 20-582, Poland

  • Istituto Neurologico Casimiro Mondino, IRCCS

    Pavia, 27100, Italy

  • Josephson Wallack Munshower Neurology P.C.

    Indianapolis, Indiana, 46256, United States

  • Kingfisher Cooperative, LLC

    Spokane, Washington, 99202, United States

  • L&C Professional Medical Research Institute

    Miami, Florida, 33144, United States

  • MD Clinical

    Hallandale, Florida, 33009, United States

  • Memory Clinic (Ottawa)

    Ottawa, Ontario, K1Z 1G3, Canada

  • Merrit Island Medical Research

    Merritt Island, Florida, 32952, United States

  • Miami Dade Medical Research Institute, LLC

    Miami, Florida, 33176, United States

  • NZOZ Neuro-Kard

    Poznan, 61-853, Poland

  • NZOZ Wielospecjalistyczna Poradnia Lekarska Synapsis

    Katowice, 40-123, Poland

  • Neural Net Research

    Portland, Oregon, 97225, United States

  • Neuro-Behavioral Clinical Research, Inc.

    North Canton, Ohio, 44321, United States

  • NeuroStudies.net, LLC

    Decatur, Georgia, 30033, United States

  • Neurology Diagnostics Inc.

    Dayton, Ohio, 45459, United States

  • Neuroscience Research Center, LLC

    Canton, Ohio, 44718, United States

  • Okanagan Clinical Trials, Ltd.

    Kelowna, British Columbia, V1Y 1Z9, Canada

  • Optimus Clinical Research

    Miami, Florida, 33125, United States

  • Ospedale San Giovanni Calibita Fatebenefratelli

    Roma, 00186, Italy

  • Podlaskie Centrum Psychogeriatrii

    Bialystok, 15-756, Poland

  • Progressive Medical Research

    Port Orange, Florida, 32127, United States

  • Re:Cognition Health

    Fairfax, Virginia, 22031, United States

  • Re:Cognition Health

    Birmingham, B16 8LT, United Kingdom

  • Re:Cognition Health

    Guildford, GU2 7YD, United Kingdom

  • Re:Cognition Health

    Plymouth, PL6 8BT, United Kingdom

  • Re:Cognition Health - Central London

    London, W1G 9JF, United Kingdom

  • Richmond Behavioral Associates

    Staten Island, New York, 10312, United States

  • Senior Clinical Trials, Inc.

    Laguna Hills, California, 92653, United States

  • Sensible Healthcare

    Ocoee, Florida, 34761, United States

  • Sharp Mesa Vista Hospital

    San Diego, California, 92123, United States

  • Stedman Clinical Trials

    Tampa, Florida, 33613, United States

  • Syrentis Clinical Research

    Santa Ana, California, 92705, United States

  • The Lindner Research Center

    Cincinnati, Ohio, 45219, United States

  • The Roskamp Institute, Inc.

    Sarasota, Florida, 34243, United States

  • Timone Adults Hospital

    Marseille, 13385, France

  • Tulsa Clinical Research LLC

    Tulsa, Oklahoma, 74136, United States

  • UBMD Neurology

    Buffalo, New York, 14203, United States

  • Universal Research Group, LLC

    Tacoma, Washington, 98405, United States

  • University of Perugia, Ospedale S.M. della Misericordia

    Perugia, 06156, Italy

  • Valley Medical Research

    Centerville, Ohio, 45459, United States

  • Visionary Investigators Network

    Aventura, Florida, 33180, United States

  • Visionary Investigators Network

    Miami, Florida, 33176, United States

  • Vitae Research Center, LLC

    Miami, Florida, 33135, United States

  • Xenoscience

    Phoenix, Arizona, 85004, United States

Conditions

Explore the condition pages connected to this study.