Major Alzheimer's trial tests new hope for slowing memory loss

NCT ID NCT06976216

Recruiting now Disease control Sponsor: Bristol-Myers Squibb Source: ClinicalTrials.gov ↗

Summary

This study aims to find out if a new drug combination called KarXT + KarX-EC can help control the memory and thinking problems caused by mild to moderate Alzheimer's disease. It will involve about 586 people who have been diagnosed with Alzheimer's and will compare the effects of the study drugs to a placebo. The main goal is to see if the treatment is safe and if it can improve or slow the decline in daily thinking skills and function.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

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Locations

A-Shine
RECRUITING

Pilsen, Plzeň-město, 301 00, Czechia

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ALPHA Recherche Clinique
RECRUITING

Québec, G3K 2P8, Canada

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AMC Research, LLC
RECRUITING

Matthews, North Carolina, 28105, United States

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Advanced Memory Research Institute of New Jersey
RECRUITING

Toms River, New Jersey, 08755, United States

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Aiginiteio University Hospital
RECRUITING

Athens, Attikí, 115 28, Greece

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Alzheimer's Research and Treatment Center
RECRUITING

Stuart, Florida, 34997, United States

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Anderson Clinical Research
RECRUITING

Redlands, California, 92374, United States

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Ascension Alexian Brothers
RECRUITING

Elk Grove Village, Illinois, 60007, United States

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Azienda Ospedaliera Spedali Civili di Brescia
RECRUITING

Brescia, 25123, Italy

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Boston Center for Memory
RECRUITING

Newton, Massachusetts, 02459, United States

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Center for Advanced Research & Education
RECRUITING

Gainesville, Georgia, 30501, United States

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Centricity Research Halifax Multispecialty
RECRUITING

Halifax, Nova Scotia, B3S 1N2, Canada

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Centrum Badan Klinicznych PI-House sp. z o.o.
RECRUITING

Gdansk, Pomeranian Voivodeship, 80-546, Poland

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Charter Research - Lady Lake
RECRUITING

The Villages, Florida, 32162, United States

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Chonnam National University Hospital
RECRUITING

Gwangju, Kwangju-Kwangyǒkshi, 61469, South Korea

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Clinica Universidad de Navarra
RECRUITING

Pamplona, Navarre, 31008, Spain

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Diex Recherche Victoriaville
RECRUITING

Victoriaville, Quebec, G6P 3Z8, Canada

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Ewha Womans University Seoul Hospital
RECRUITING

Seoul, Seoul-teukbyeolsi [Seoul], 07804, South Korea

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Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico
RECRUITING

Milan, Lombardy, 20122, Italy

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Fundación Lennox - Instituto Modelo de Neurología
RECRUITING

Córdoba, 5000, Argentina

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Gadolin Research
RECRUITING

Beaumont, Texas, 77702, United States

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Georgetown University Medical Center
RECRUITING

Washington D.C., District of Columbia, 20007, United States

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Hanyang University Seoul Hospital
RECRUITING

Seoul, Seoul-teukbyeolsi [Seoul], 04763, South Korea

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HealthPartners Neuroscience Center
RECRUITING

Saint Paul, Minnesota, 55130, United States

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Healthy Brain Clinic
RECRUITING

Long Beach, California, 90804, United States

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Hospital Clinico San Carlos
RECRUITING

Madrid, 28040, Spain

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Hospital Clínic de Barcelona
RECRUITING

Barcelona, Catalunya [Cataluña], 08036, Spain

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Hospital Universitari General de Catalunya
RECRUITING

Sant Cugat del Vallès, Barcelona [Barcelona], 08915, Spain

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Hospital Universitari de Santa Maria
RECRUITING

Lleida, Lleida [Lérida], 25198, Spain

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Hospital Victoria Eugenia
RECRUITING

Seville, Andalusia, 41009, Spain

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Hospital das Clinicas FMUSP
RECRUITING

São Paulo, 05403-000, Brazil

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Institut neuropsychiatricke pece (INEP), Praha
RECRUITING

Prague, Praha 8, 18600, Czechia

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Instituto Kremer
RECRUITING

Córdoba, X5004AOA, Argentina

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JEM Research Institute
RECRUITING

Atlantis, Florida, 33462, United States

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KARA Institute for Neurological Diseases
RECRUITING

Macquarie Park, New South Wales, 2113, Australia

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Konkuk University Medical Center
RECRUITING

Seoul, Seoul-teukbyeolsi [Seoul], 05030, South Korea

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Local Institution - 0001
NOT_YET_RECRUITING

Buenos Aires, Buenos Aires F.D., 1133, Argentina

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Local Institution - 0004
WITHDRAWN

Abington, Pennsylvania, 19001, United States
Local Institution - 0016
WITHDRAWN

Columbus, Georgia, 31909, United States
Local Institution - 0088
NOT_YET_RECRUITING

Banfield, Buenos Aires, B1828CKR, Argentina

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Local Institution - 0089
NOT_YET_RECRUITING

Santiago, Santiago Metropolitan, 7560356, Chile

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Local Institution - 0094
NOT_YET_RECRUITING

Santiago, Santiago Metropolitan, 7500710, Chile

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Local Institution - 0101
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New York, New York, 10016, United States

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Local Institution - 0168
NOT_YET_RECRUITING

Brasília, Federal District, 70200730, Brazil

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Local Institution - 0180
NOT_YET_RECRUITING

Curitiba, Paraná, 81210310, Brazil

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Local Institution - 0181
NOT_YET_RECRUITING

San Juan, 00918, Puerto Rico

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Local Institution - 0215
NOT_YET_RECRUITING

Zagreb, City of Zagreb, 10000, Croatia

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Local Institution - 0216
NOT_YET_RECRUITING

Osijek, 31000, Croatia

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Local Institution - 0218
NOT_YET_RECRUITING

Berlin, 13125, Germany

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Local Institution - 0219
NOT_YET_RECRUITING

Münster, North Rhine-Westphalia, 48149, Germany

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Local Institution - 0225
NOT_YET_RECRUITING

Olomouc, Olomoucký kraj, 779 00, Czechia

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Local Institution - 0230
NOT_YET_RECRUITING

Antofagasta, AN, 1270244, Chile

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Local Institution - 0240
NOT_YET_RECRUITING

Zagreb, 10090, Croatia

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Local Institution - 0241
NOT_YET_RECRUITING

Santiago, Santiago Metropolitan, 8380420, Chile

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Local Institution - 0244
NOT_YET_RECRUITING

Darlinghurst, 2010, Australia

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Local Institution - 0248
NOT_YET_RECRUITING

Monza, Lombardy, 20900, Italy

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Local Institution - 0251
NOT_YET_RECRUITING

Thessaloniki, Thessaloníki, 546 36, Greece

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Local Institution - 0256
WITHDRAWN

Athens, Attikí, 115 25, Greece
Local Institution - 0257
NOT_YET_RECRUITING

Larissa, Thessalía, 41110, Greece

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Local Institution - 0259
ACTIVE_NOT_RECRUITING

New York, New York, 10029, United States
Local Institution - 0261
NOT_YET_RECRUITING

Torun, Kuyavian-Pomeranian Voivodeship, 87-100, Poland

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Local Institution - 0262
NOT_YET_RECRUITING

Poznan, Greater Poland Voivodeship, 61-485, Poland

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Local Institution - 0266
NOT_YET_RECRUITING

Aracaju, Sergipe, 49075-000, Brazil

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Local Institution - 0267
NOT_YET_RECRUITING

Rijeka, 51000, Croatia

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Local Institution - 0268
NOT_YET_RECRUITING

Iași, 700282, Romania

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Local Institution - 0271
NOT_YET_RECRUITING

Buenos Aires, 1280, Argentina

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Local Institution - 0272
NOT_YET_RECRUITING

Providencia, Santiago Metropolitan, 7500504, Chile

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Local Institution - 0273
NOT_YET_RECRUITING

Bucharest, București, 041914, Romania

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Local Institution - 0275
WITHDRAWN

Hamburg, 20246, Germany
Local Institution - 0276
NOT_YET_RECRUITING

Mainz, Rhineland-Palatinate, 55131, Germany

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Local Institution - 0277
NOT_YET_RECRUITING

Bremen, 28325, Germany

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Local Institution - 0278
NOT_YET_RECRUITING

Bucharest, București, 011241, Romania

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Local Institution - 0279
NOT_YET_RECRUITING

Kogarah, New South Wales, 2217, Australia

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Local Institution - 0282
NOT_YET_RECRUITING

Hyderabad, Telangana, 500034, India

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Local Institution - 0284
NOT_YET_RECRUITING

Zagreb, City of Zagreb, 10000, Croatia

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Local Institution - 0285
NOT_YET_RECRUITING

Hyderabad, Telangana, 500082, India

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Local Institution - 0286
NOT_YET_RECRUITING

Kolkata, West Bengal, 700054, India

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Local Institution - 0287
NOT_YET_RECRUITING

Varanasi, Uttar Pradesh, 221005, India

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Local Institution - 0288
NOT_YET_RECRUITING

Bengaluru, Karnataka, 560029, India

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Merritt Island Medical Research, LLC
RECRUITING

Merritt Island, Florida, 32952, United States

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MlynowaMed Psychiatric
RECRUITING

Bialystok, Podlaskie Voivodeship, 15-404, Poland

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MoCA Research and Innovation Inc.
RECRUITING

Greenfield Park, Quebec, J4V 2J2, Canada

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Mountain Neurological Research Center
RECRUITING

Basalt, Colorado, 81621, United States

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Neuro Health Centrum
RECRUITING

Brno, Brno-město, 628 00, Czechia

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NeuroCentrix
RECRUITING

Carlton, Victoria, 3053, Australia

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Neurodegenerative Disorders Research
RECRUITING

Perth, Western Australia, 6005, Australia

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Neurologická Ambulance - Forbeli
RECRUITING

Prague, Praha 6, 160 00, Czechia

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Neurology Clinic, P.C.
RECRUITING

Cordova, Tennessee, 38018, United States

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Neurology Diagnostics, Inc.
RECRUITING

Dayton, Ohio, 45459, United States

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Neuropsychiatrie
RECRUITING

Prague, Praha 6, 160 00, Czechia

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OCT Research ULC
RECRUITING

Kelowna, British Columbia, V1Y 1Z9, Canada

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Ohio State University
RECRUITING

Columbus, Ohio, 43221, United States

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Ospedale San Raffaele
RECRUITING

Milan, Lombardy, 20132, Italy

Contact Phone: •••-•••-••••
Ottawa Memory Clinic
RECRUITING

Ottawa, Ontario, K1Z 1G3, Canada

Contact Phone: •••-•••-••••
Prof. Dr. Alexandru Obregia Psychiatry Hospital
RECRUITING

Bucharest, București, 041914, Romania
Prof. Dr. Alexandru Obregia Psychiatry Hospital
RECRUITING

Bucharest, București, 041914, Romania

Contact Phone: •••-•••-••••

Contact Phone: •••-•••-••••
Re:Cognition Health - Chicago
RECRUITING

Chicago, Illinois, 60611, United States

Contact Phone: •••-•••-••••
Renstar Medical Research
RECRUITING

Ocala, Florida, 34470, United States

Contact Phone: •••-•••-••••
Rhode Island Mood & Memory Research Institute
RECRUITING

East Providence, Rhode Island, 02914, United States

Contact Phone: •••-•••-••••
Richmond Clinical Trials
RECRUITING

Richmond, British Columbia, V6V 2L1, Canada

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SUNY Upstate Medical University
RECRUITING

Syracuse, New York, 13210, United States

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Samsung Medical Center
RECRUITING

Seoul, Seoul-teukbyeolsi [Seoul], 06351, South Korea

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Sanatorio Morra S.A.
RECRUITING

Córdoba, 5000, Argentina

Contact Phone: •••-•••-••••
Seoul National University Bundang Hospital
RECRUITING

Seongnam, Kyǒnggi-do, 13620, South Korea

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Seoul National University Hospital
RECRUITING

Seoul, Seoul-teukbyeolsi [Seoul], 03080, South Korea

Contact Phone: •••-•••-••••
Summit Headlands
RECRUITING

Portland, Oregon, 97210, United States

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TUM Klinikum
RECRUITING

München, Bavaria, 81675, Germany

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Toronto Memory Program
RECRUITING

Toronto, Ontario, M3B 2S7, Canada

Contact Phone: •••-•••-••••
University General Hospital of Alexandroupoli
RECRUITING

Alexandroupoli, Anatolikí Makedonía Kai Thráki, 681 00, Greece

Contact Phone: •••-•••-••••
VIN-Julie Schwartzbard
RECRUITING

Aventura, Florida, 33180, United States

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Vestra Clinics
RECRUITING

Rychnov nad Kněžnou, 516 01, Czechia

Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.

ALZHEIMER'S DISEASE