Major Alzheimer's trial tests promising drug duo to slow memory loss

NCT ID NCT06976203

Recruiting now Disease control Sponsor: Bristol-Myers Squibb Source: ClinicalTrials.gov ↗

Summary

This study is testing whether a two-drug combination called KarXT + KarX-EC can help improve thinking and memory problems in people with mild to moderate Alzheimer's disease. Researchers will compare the drug combination against a placebo in 586 participants over several months to see if it's safe and effective. The study focuses on measuring changes in cognitive function, daily living abilities, and behavioral symptoms.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

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Locations

Advanced Clinical Institute
RECRUITING

West Long Branch, New Jersey, 07764, United States

Contact Phone: •••-•••-••••
Alzheimer's Research and Treatment Center
RECRUITING

Wellington, Florida, 33414, United States

Contact Phone: •••-•••-••••
Assistance Publique Hôpitaux de Marseille - Hôpital de la Timone
RECRUITING

Marseille, Bouches-du-Rhône, 13005, France

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Assistance Publique Hôpitaux de Paris - Groupe Hospitalier 10e - Hôpital Lariboisière
RECRUITING

Paris, 75010, France

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Austin Health
RECRUITING

Ivanhoe, Victoria, 3079, Australia

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Azienda Ospedaliero Universitaria Policlinico Riuniti di Foggia
RECRUITING

Foggia, 71100, Italy

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Bordeaux University Hospital - Pellegrin
RECRUITING

Bordeaux, 33076, France

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Brain Research Center
RECRUITING

Amsterdam, North Holland, 1081 GN, Netherlands

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Brain Research Center Den Bosch B.V.
RECRUITING

's-Hertogenbosch, North Brabant, 5223 LA, Netherlands

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Brain Research Center Zwolle
RECRUITING

Zwolle, Overijssel, 8025 AZ, Netherlands

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CEN Centro Especializado en Neurociencias
RECRUITING

Córdoba, 5000, Argentina

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CRST Helsinki Oy
RECRUITING

Helsinki, Uusimaa, 00180, Finland

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Campus Neurológico Sénior
RECRUITING

Torres Vedras, Lisbon District, 2560-280, Portugal

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Central Texas Neurology Consultants, PA
RECRUITING

Round Rock, Texas, 78681, United States

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Centre Hospitalier Régional Universitaire de Lille - Hôpital Roger Salengro
RECRUITING

Lille, Hauts-de-France, 59037, France

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Centre Hospitalier Universitaire Régional de Nancy
RECRUITING

Nancy, Meurthe-et-Moselle, 54035, France

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Centre Hospitalier Universitaire Toulouse - Cité de la Santé
RECRUITING

Toulouse, Haute-Garonne, 31000, France

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Centre Hospitalier Universitaire de Rennes - Hôpital Pontchaillou
RECRUITING

Rennes, Ille-et-Vilaine, 35000, France

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Centro Médico Luquez
RECRUITING

Córdoba, Córdoba Province, X5006CBI, Argentina

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Clinical Research Services Turku
RECRUITING

Turku, Southwest Finland, 20520, Finland

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Complejo Hospitalario Ruber Juan Bravo
RECRUITING

Madrid, 28006, Spain

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Dent Neurosciences Research Center, Inc
RECRUITING

Amherst, New York, 14226, United States

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EMC Silesia sp. z o.o.
RECRUITING

Katowice, Silesian Voivodeship, 40-353, Poland

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Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro Cuore
RECRUITING

Roma, 00168, Italy

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Fullerton Neurology and Headache Center
RECRUITING

Fullerton, California, 92835, United States

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Fundació ACE
RECRUITING

Barcelona, Barcelona [Barcelona], 08028, Spain

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Great Lakes Clinical Trials - Andersonville
RECRUITING

Chicago, Illinois, 60640, United States

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Griffith University - Gold Coast Campus
RECRUITING

Southport, Queensland, 4222, Australia

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Hospices Civils de Lyon - Hôpital Pierre Wertheimer
RECRUITING

Bron, Rhône, 69500, France

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Hospital Universitario 12 de Octubre
RECRUITING

Madrid, 28041, Spain

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Hospital Universitario Doctor Peset
RECRUITING

Valencia, Valenciana, Comunitat, 46017, Spain

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Hospital Universitario Marqués de Valdecilla
RECRUITING

Santander, Cantabria, 39008, Spain

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Hospital Universitario Quironsalud Madrid
RECRUITING

Pozuelo de Alarcón, Madrid, 28223, Spain

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Hospital de Braga
RECRUITING

Braga, 4710-243, Portugal

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Hygeia Hospital
RECRUITING

Marousi, Attikí, 151 23, Greece

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Hôpital Broca
RECRUITING

Paris, 75013, France

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Inglewood Clinical
RECRUITING

Inglewood, California, 90301, United States

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Instytut Zdrowia Dr Boczarska Jedynak
RECRUITING

Oświęcim, Lesser Poland Voivodeship, 32-600, Poland

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Intercoastal Medical Group
RECRUITING

Sarasota, Florida, 34239, United States

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Irvine Clinical Research
RECRUITING

Irvine, California, 92614, United States

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Itä-Suomen Yliopisto Kuopio
RECRUITING

Kuopio, 70210, Finland

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Jacksonville Center for Clinical Research
RECRUITING

Jacksonville, Florida, 32216, United States

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Josephson Wallack Munshower Neurology, PC
RECRUITING

Indianapolis, Indiana, 46256, United States

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K2 MEDICAL Research THE VILLAGES
RECRUITING

Lady Lake, Florida, 32159, United States

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Katayama Medical Clinic
RECRUITING

Kurashiki, Okayama-ken, 710-0813, Japan

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Keystone Clinical Studies
RECRUITING

Plymouth Meeting, Pennsylvania, 19462, United States

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Kokankai Kokan Clinic
RECRUITING

Kawasaki, Kanagawa, 2100852, Japan

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Les Hôpitaux Universitaires de Strasbourg - Hôpital de la Robertsau
RECRUITING

Strasbourg, 67091, France

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Local Institution - 0004
NOT_YET_RECRUITING

Munich, Bavaria, 80539, Germany

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Local Institution - 0017
WITHDRAWN

Villefranche-sur-Saône, Rhône, 69655, France
Local Institution - 0025
NOT_YET_RECRUITING

Buenos Aires, C1428AQK, Argentina

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Local Institution - 0026
NOT_YET_RECRUITING

Mendoza, 5502, Argentina

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Local Institution - 0029
NOT_YET_RECRUITING

ABB, Buenos Aires F.D., 1181, Argentina

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Local Institution - 0030
NOT_YET_RECRUITING

Córdoba, X5003DCE, Argentina

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Local Institution - 0037
WITHDRAWN

Wako, Saitama, 351-0111, Japan
Local Institution - 0038
NOT_YET_RECRUITING

Ina, Nagano, 396-0033, Japan

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Local Institution - 0041
NOT_YET_RECRUITING

Sanpetru /Brasov, 507190, Romania

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Local Institution - 0042
NOT_YET_RECRUITING

Bucharest, 0, Romania

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Local Institution - 0049
NOT_YET_RECRUITING

Coimbra, 3000 075, Portugal

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Local Institution - 0052
NOT_YET_RECRUITING

Porto, 4050-014, Portugal

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Local Institution - 0053
NOT_YET_RECRUITING

Sippy Downs, Queensland, 4556, Australia

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Local Institution - 0055
NOT_YET_RECRUITING

Saint Lucia, Queensland, 4072, Australia

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Local Institution - 0059
NOT_YET_RECRUITING

Ioannina, Ioánnina, 455 00, Greece

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Local Institution - 0063
NOT_YET_RECRUITING

Guimarães, 4800-055, Portugal

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Local Institution - 0064
NOT_YET_RECRUITING

Wroclaw, Lower Silesian Voivodeship, 54-239, Poland

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Local Institution - 0069
WITHDRAWN

San Diego, California, 92103, United States
Local Institution - 0078
WITHDRAWN

Lake Success, New York, 11042, United States
Local Institution - 0080
NOT_YET_RECRUITING

Watertown, Massachusetts, 02472, United States

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Local Institution - 0081
NOT_YET_RECRUITING

Dallas, Texas, 75231, United States

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Local Institution - 0083
NOT_YET_RECRUITING

Palo Alto, California, 94304, United States

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Local Institution - 0099
NOT_YET_RECRUITING

Rio de Janeiro, 22270-060, Brazil

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Local Institution - 0100
NOT_YET_RECRUITING

São Paulo, 01228-000, Brazil

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Local Institution - 0101
NOT_YET_RECRUITING

Maringá, Paraná, 87015-180, Brazil

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Local Institution - 0103
NOT_YET_RECRUITING

Edinburgh, Midlothian, EH4 2XU, United Kingdom

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Local Institution - 0104
NOT_YET_RECRUITING

Matosinhos Municipality, Porto District, 4464-513, Portugal

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Local Institution - 0107
NOT_YET_RECRUITING

Kyoto, 616-8255, Japan

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Local Institution - 0108
NOT_YET_RECRUITING

Lublin, Lublin Voivodeship, 20-064, Poland

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Local Institution - 0109
NOT_YET_RECRUITING

Pátrai, Achaḯa, 26504, Greece

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Local Institution - 0110
NOT_YET_RECRUITING

Thessaloniki, 546 36, Greece

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Local Institution - 0111
NOT_YET_RECRUITING

Kippax, Leeds, LS25 7JN, United Kingdom

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Local Institution - 0113
NOT_YET_RECRUITING

Constanța, Constanța County, 900675, Romania

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Local Institution - 0115
NOT_YET_RECRUITING

Fortaleza, Ceará, 60135-237, Brazil

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Local Institution - 0119
WITHDRAWN

Ridgewood, New Jersey, 07450, United States
Local Institution - 0120
NOT_YET_RECRUITING

Kita, Kagawa-ken, 761-0701, Japan

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Local Institution - 0121
NOT_YET_RECRUITING

Inage, Chiba, 263-0043, Japan

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Local Institution - 0123
NOT_YET_RECRUITING

Matsudo, Chiba, 271-0047, Japan

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Local Institution - 0124
NOT_YET_RECRUITING

Higashihiroshima, Hiroshima, 732-0066, Japan

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NIHR Manchester Clinical Research Facility
RECRUITING

Manchester, England, M13 9WL, United Kingdom

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National Hospital Organization Hizen Psychiatric Center
RECRUITING

Yoshinogari-cho, Kanzaki-gun, Saga-ken, 842-0192, Japan

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National Hospital Organization Niigata Hospital
RECRUITING

Kashiwazaki, Niigata, 945-8585, Japan

Contact Phone: •••-•••-••••
Neurological Associates Albany
RECRUITING

Albany, New York, 12208, United States

Contact Phone: •••-•••-••••
Neuropsychiatric Research Center of Southwest Florida
RECRUITING

Fort Myers, Florida, 33912, United States

Contact Phone: •••-•••-••••
Nippon Medical School Musashi Kosugi Hospital
RECRUITING

Kawasaki, Kanagawa, 211-8533, Japan

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Pharmakologisches Studienzentrum Chemnitz
RECRUITING

Chemnitz, 09111, Germany

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Pitie Salpetriere University Hospital
RECRUITING

Paris, 75013, France

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Policlinica Gipuzkoa
RECRUITING

Donostia / San Sebastian, Basque Country, 20014, Spain

Contact Phone: •••-•••-••••
Private Practice - Dr. Irma Schöll
RECRUITING

Bad Homburg, 61348, Germany

Contact Phone: •••-•••-••••
Private Practice - Dr. Ronald Louis Schwartz
RECRUITING

Hattiesburg, Mississippi, 39401, United States

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Prof. Dr. Alexandru Obregia Psychiatry Hospital
RECRUITING

Bucharest, București, 041914, Romania
Prof. Dr. Alexandru Obregia Psychiatry Hospital
RECRUITING

Bucharest, București, 041914, Romania

Contact Phone: •••-•••-••••

Contact Phone: •••-•••-••••
QUEST Research Institute
RECRUITING

Farmington Hills, Michigan, 48334, United States

Contact Phone: •••-•••-••••
Rainier Clinical Research Center
RECRUITING

Renton, Washington, 98057, United States

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Re:Cognition Health - Birmingham
RECRUITING

Birmingham, B16 8LT, United Kingdom

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Research of the Rockies
RECRUITING

Colorado Springs, Colorado, 80919, United States

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SCB Research Center
RECRUITING

Bayamón, 00961, Puerto Rico

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Southern Illinois University School of Medicine
RECRUITING

Springfield, Illinois, 62702, United States

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Terveystalo Oulu
RECRUITING

Oulu, North Ostrobothnia, 90100, Finland

Contact Phone: •••-•••-••••
Terveystalo Ruoholahti
RECRUITING

Helsinki, 00180, Finland

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The Cognitive and Research Center of New Jersey
RECRUITING

Springfield, New Jersey, 07081, United States

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The Maudsley Hospital
RECRUITING

London, London, City of, SE5 8AZ, United Kingdom

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Tominaga Clinic
RECRUITING

Osaka, Osaka, 5560015, Japan

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USF Health Byrd Alzheimer's Institute
RECRUITING

Tampa, Florida, 33613, United States

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Universitaetsklinikum Koeln
RECRUITING

Cologne, 50937, Germany

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Universitaetsklinikum Ulm
RECRUITING

Ulm, 89081, Germany

Contact Phone: •••-•••-••••
University General Hospital "ATTIKON" - General Hospital of West Attica "H AGIA VARVARA"
RECRUITING

Chaïdári, Attikí, 124 62, Greece

Contact Phone: •••-•••-••••
University at Buffalo - UBMD Neurology
RECRUITING

Buffalo, New York, 14203, United States

Contact Phone: •••-•••-••••
University of Naples Federico II
RECRUITING

Naples, Campania, 80131, Italy

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Universitätsmedizin Göttingen - Georg-August-Universität
RECRUITING

Göttingen, Lower Saxony, 37075, Germany

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Velocity Clinical Research, Hallandale Beach
RECRUITING

Hallandale, Florida, 33009, United States

Contact
Wako Hospital
RECRUITING

Wako, Saitama, 351-0111, Japan

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Warneford Hospital
RECRUITING

Oxford, Oxfordshire, OX3 7JX, United Kingdom

Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.

ALZHEIMER'S DISEASE