Scientists map the Brain's journey to Alzheimer's in landmark study

NCT ID NCT02854033

Completed Knowledge-focused Sponsor: University of Southern California Source: ClinicalTrials.gov ↗

Summary

This study aimed to understand how Alzheimer's disease develops by tracking changes in the brain over time. It followed over 1,100 older adults, some healthy, some with mild memory issues, and some with early Alzheimer's, for up to five years. Researchers used brain scans, memory tests, and fluid samples to identify markers that could help design better future treatment trials.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Albany Medical College

Albany, New York, 12208, United States
Banner Alzheimer's Institute

Phoenix, Arizona, 85006, United States
Banner Sun Health Research Institute

Sun City, Arizona, 85351, United States
Barrow Neurological Institute

Phoenix, Arizona, 85013, United States
Baylor College of Medicine

Houston, Texas, 77030, United States
Boston University School of Medicine

Boston, Massachusetts, 21182307, United States
Brigham and Women's Hospital

Boston, Massachusetts, 21155804, United States
Butler Hospital Memory and Aging Program

Providence, Rhode Island, 02906, United States
Case Western Reserve University

Beachwood, Ohio, 441224312, United States
Cleveland Clinic Lou Ruvo Center for Brain Health

Las Vegas, Nevada, 891060100, United States
Columbia University

New York, New York, 10032, United States
Dent Neurologic Institute

Buffalo, New York, 142261727, United States
Duke University Medical Center

Durham, North Carolina, 27710, United States
Emory University

Atlanta, Georgia, 30322, United States
Georgetown University

Washington D.C., District of Columbia, 200072145, United States
Houston Methodist

Houston, Texas, 77030, United States
Howard University

Washington D.C., District of Columbia, 200600001, United States
Indiana University

Indianapolis, Indiana, 46202, United States
Jewish General Hospital Memory Clinic

Montreal, Quebec, H3T 1E2, Canada
Johns Hopkins University

Baltimore, Maryland, 212242764, United States
Long Beach VA Neuropsychiatric Research Program

Long Beach, California, 90822, United States
Mayo Clinic, Jacksonville

Jacksonville, Florida, 32224, United States
Mayo Clinic, Rochester

Rochester, Minnesota, 559050001, United States
Mount Sinai School of Medicine

New York, New York, 100296552, United States
Nathan Kline Institute for Psychiatric Research

Orangeburg, New York, 109621159, United States
New York University Medical Center

New York, New York, 100166055, United States
Northwestern University

Chicago, Illinois, 606113010, United States
Ohio State University

Columbus, Ohio, 43210, United States
Oregon Health & Science University

Portland, Oregon, 972393011, United States
Parkwood Institute

London, Ontario, N6C 0A7, Canada
Ralph H. Johnson VA Health Care System

Charleston, South Carolina, 29401, United States
Rhode Island Hospital

Providence, Rhode Island, 02903, United States
Rush University Medical Center

Chicago, Illinois, 606123806, United States
St. Joseph's Health Center - Cognitive Neurology

London, Ontario, N6C 4R3, Canada
Sunnybrook Health Sciences Centre

Toronto, Ontario, M4N 3M5, Canada
University of Alabama, Birmingham

Birmingham, Alabama, 35294, United States
University of British Columbia, Clinic for AD & Related

Vancouver, British Columbia, V6T1Z3, Canada
University of California, Davis

Walnut Creek, California, 945985900, United States
University of California, Irvine

Irvine, California, 92697, United States
University of California, Los Angeles

Los Angeles, California, 90095, United States
University of California, San Diego

La Jolla, California, 920371707, United States
University of California, San Francisco

San Francisco, California, 94158, United States
University of Iowa

Iowa City, Iowa, 52242, United States
University of Kansas

Fairway, Kansas, 66205, United States
University of Kentucky

Lexington, Kentucky, 405042681, United States
University of Michigan, Ann Arbor

Ann Arbor, Michigan, 481052967, United States
University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States
University of Pittsburgh

Pittsburgh, Pennsylvania, 15213, United States
University of Rochester

Rochester, New York, 14620, United States
University of South Florida - Health Byrd Alzheimer Institute

Tampa, Florida, 336134808, United States
University of Southern California

Los Angeles, California, 900335310, United States
University of Texas, Southwestern MC at Dallas

Dallas, Texas, 75390, United States
University of Wisconsin

Madison, Wisconsin, 537920001, United States
VA Palo Alto HSC / Stanford School of Medicine

Palo Alto, California, 94304, United States
Vanderbilt University Medical Center

Nashville, Tennessee, 37212, United States
Wake Forest University Health Sciences

Winston-Salem, North Carolina, 27157, United States
Washington University, St. Louis

St Louis, Missouri, 631082215, United States
Wien Center for Clinical Research

Miami Beach, Florida, 331402877, United States
Yale University School of Medicine

New Haven, Connecticut, 65103330, United States

Conditions

Explore the condition pages connected to this study.

ALZHEIMER'S DISEASE (AD) MILD COGNITIVE IMPAIRMENT(MCI)