New drug trial aims to strengthen bones in kids with rare genetic disorder

NCT ID NCT06079359

Summary

This study is testing whether an experimental drug called ALXN1850 can improve bone health and physical abilities in children aged 2-12 with hypophosphatasia, a rare genetic condition that weakens bones. Participants receive either the drug or a placebo through injections under the skin for about 6 months. Researchers measure changes in bone X-rays, walking distance, and motor skills to see if the treatment helps.

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Contacts and locations

Locations

  • Research Site

    Baltimore, Maryland, 21287, United States

  • Research Site

    Kansas City, Missouri, 64108, United States

  • Research Site

    Durham, North Carolina, 27705, United States

  • Research Site

    Nedlands, 6009, Australia

  • Research Site

    Parkville, 3052, Australia

  • Research Site

    Brussels, 1020, Belgium

  • Research Site

    Brasília, 71625-009, Brazil

  • Research Site

    Porto Alegre, 90610-261, Brazil

  • Research Site

    Recife, 50740-465, Brazil

  • Research Site

    Salvador, 40050-410, Brazil

  • Research Site

    São Paulo, 01409-902, Brazil

  • Research Site

    São Paulo, 05403-900, Brazil

  • Research Site

    Calgary, Alberta, T2E 7Z4, Canada

  • Research Site

    Winnepeg, Manitoba, R3E 3P4, Canada

  • Research Site

    Beijing, 100045, China

  • Research Site

    Guangzhou, 510623, China

  • Research Site

    Shanghai, 2000127, China

  • Research Site

    Shenzhen, 518053, China

  • Research Site

    Helsinki, 00290, Finland

  • Research Site

    Ashkelon, 7830604, Israel

  • Research Site

    Chihuahua City, 31238, Mexico

  • Research Site

    Lodz, 93-338, Poland

  • Research Site

    Bucharest, 011863, Romania

  • Research Site

    Madrid, 28046, Spain

  • Research Site

    Vitoria-Gasteiz, 01009, Spain

  • Research Site

    Stockholm, 17176, Sweden

  • Research Site

    Taipei, 100, Taiwan

  • Research Site

    Ankara, 06560, Turkey (Türkiye)

  • Research Site

    Bursa, 16059, Turkey (Türkiye)

  • Research Site

    Erzurum, 25240, Turkey (Türkiye)

  • Research Site

    Istanbul, 34899, Turkey (Türkiye)

  • Research Site

    Birmingham, B4 6NH, United Kingdom

Conditions

Explore the condition pages connected to this study.