New drug trial aims to strengthen bones in kids with rare genetic disorder

NCT ID NCT06079359

Ongoing Disease control Sponsor: Alexion Pharmaceuticals, Inc. Source: ClinicalTrials.gov ↗

Summary

This study is testing whether an investigational drug called ALXN1850 can help children with hypophosphatasia, a rare genetic disorder that causes soft, weak bones. Over 169 days, researchers will compare ALXN1850 to a placebo (inactive substance) to see if it improves bone healing on X-rays, walking ability, and motor skills. The goal is to control the disease and improve physical function in children aged 2 to under 12 who haven't had previous treatment.

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Contacts and locations

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Locations

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Baltimore, Maryland, 21287, United States
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Kansas City, Missouri, 64108, United States
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Durham, North Carolina, 27705, United States
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Nedlands, 6009, Australia
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Parkville, 3052, Australia
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Brussels, 1020, Belgium
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Brasília, 71625-009, Brazil
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Porto Alegre, 90610-261, Brazil
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Recife, 50740-465, Brazil
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Salvador, 40050-410, Brazil
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São Paulo, 01409-902, Brazil
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São Paulo, 05403-900, Brazil
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Calgary, Alberta, T2E 7Z4, Canada
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Winnepeg, Manitoba, R3E 3P4, Canada
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Beijing, 100045, China
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Guangzhou, 510623, China
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Shanghai, 2000127, China
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Shenzhen, 518053, China
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Helsinki, 00290, Finland
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Ashkelon, 7830604, Israel
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Chihuahua City, 31238, Mexico
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Lodz, 93-338, Poland
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Bucharest, 011863, Romania
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Madrid, 28046, Spain
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Vitoria-Gasteiz, 01009, Spain
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Stockholm, 17176, Sweden
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Taipei, 100, Taiwan
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Ankara, 06560, Turkey (Türkiye)
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Bursa, 16059, Turkey (Türkiye)
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Erzurum, 25240, Turkey (Türkiye)
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Istanbul, 34899, Turkey (Türkiye)
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Birmingham, B4 6NH, United Kingdom

Conditions

Explore the condition pages connected to this study.

HYPOPHOSPHATASIA