New hope for tough colitis cases: experimental drug enters mid-stage trial

NCT ID NCT06109441

First seen Jan 05, 2026 · Last updated May 08, 2026 · Updated 16 times

Summary

This study tests an experimental drug called ALTB-268 in 50 adults with moderate-to-severe ulcerative colitis that did not improve with biologic therapies. The goal is to see if the drug can reduce disease activity, measured by a standard score. Participants receive the drug openly (everyone knows they are getting it) and are followed for at least 12 weeks, with a long-term extension option.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Alliance Clinical Research of Tampa, LLC.

    Tampa, Florida, 33615, United States

  • Caprock Gastro Reasearch

    Lubbock, Texas, 19424, United States

  • DHAT / GI Aliance

    Garland, Texas, 75044, United States

  • Dayton Gastroenterology, LLC

    Beavercreek, Ohio, 45440, United States

  • Digestive Disease Medicine of Central New York

    Utica, New York, 13502, United States

  • Digestive and Liver Center of Florida, LLC

    Orlando, Florida, 32825, United States

  • Frontier Clinical Research, LLC

    Uniontown, Pennsylvania, 15401, United States

  • GI Alliance

    Mansfield, Texas, 760603, United States

  • GI Alliance

    Webster, Texas, 33016, United States

  • Gastro Health Ohio

    Liberty Township, Ohio, 45044, United States

  • Gastro Health Partners Louisville

    Louisville, Kentucky, 40218, United States

  • Gastro Health Partners Southern Indiana

    New Albany, Indiana, 47150, United States

  • Gastro Health Research

    Miami, Florida, 33176, United States

  • Gastroenterology Associates of North Mississippi

    Oxford, Mississippi, 38655, United States

  • Gastroenterology Associates, P.A.

    Greenville, South Carolina, 29607, United States

  • Gastroenterology Group of Rochester

    Rochester, New York, 14618, United States

  • Louisiana Research Center, LLC.

    Shreveport, Louisiana, 71105, United States

  • New York Presbyterian Hospital - Weill Cornell Medical Colllege

    New York, New York, 10065, United States

  • Rocky Mountain Gastroenterology

    Littleton, Colorado, 80120, United States

  • San Diego Gastroenterology

    San Diego, California, 92103, United States

  • Southern Star Research Institute LLC

    San Antonio, Texas, 78229, United States

  • Tyler Research Institute

    Tyler, Texas, 75701, United States

  • Wellness Clinical Research, LLC

    Vega Baja, 00693, Puerto Rico

  • Wisconsin Center for Advanced Research

    Milwaukee, Wisconsin, 53215, United States

Conditions

Explore the condition pages connected to this study.