New drug combo aims to slow ALS in landmark trial
NCT ID NCT07161999
First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 30 times
Summary
This study tests an experimental drug called COYA 302 in 120 adults with ALS. The treatment combines two substances to calm the immune system and reduce nerve damage. Participants will receive either the drug or a placebo for 24 weeks, and may continue on the drug for another 24 weeks. The goal is to see if COYA 302 can slow disease progression and improve breathing and daily function.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Austin Neuromuscular Center; National Neuromuscular Research Institute, PLLC
RECRUITINGAustin, Texas, 78759, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Barrow Neurological Institute
RECRUITINGPhoenix, Arizona, 85013, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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California Pacific Medical Center
RECRUITINGSan Francisco, California, 94110, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Cedars-Sinai Medical Center
RECRUITINGLos Angeles, California, 90048, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Columbia University Medical Center ALS Center
RECRUITINGNew York, New York, 10032, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Emory University
RECRUITINGAtlanta, Georgia, 30322, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hopital Neurologique de Montreal
RECRUITINGMontreal, Quebec, H3A 2B4, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Houston Methodist Stanley H. Appel Department of Neurology
RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Johns Hopkins
RECRUITINGBaltimore, Maryland, 21287, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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London Health Sciences Center
RECRUITINGLondon, Ontario, N6A 3K7, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Neurology Associates, P.C. Somnos Clinical Research
ACTIVE_NOT_RECRUITINGLincoln, Nebraska, 68510, United States
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Northwestern
RECRUITINGChicago, Illinois, 60611, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Nova Southeastern University
RECRUITINGDavie, Florida, 33314, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Temple Neurology
RECRUITINGPhiladelphia, Pennsylvania, 19140, United States
Contact Email: •••••@•••••
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Texas Neurology, PA
RECRUITINGDallas, Texas, 75206, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The University of Texas Health Science Center
RECRUITINGSan Antonio, Texas, 78229, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Thomas Jefferson University-Weinberg ALS Center
RECRUITINGPhiladelphia, Pennsylvania, 19107, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University Of Miami
RECRUITINGMiami, Florida, 33136, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of British Columbia
RECRUITINGVancouver, British Columbia, V6T1Z3, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Florida Clinical and Translational Research Center
RECRUITINGGainesville, Florida, 32610, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Michigan
RECRUITINGAnn Arbor, Michigan, 48109, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of South Florida
RECRUITINGTampa, Florida, 33612, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Toronto/Sunnybrook Health Sciences Center
RECRUITINGToronto, Ontario, M5S 3H2, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Washington University
RECRUITINGSt Louis, Missouri, 63110, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.