ALS drug edaravone put to the test in extended trial
NCT ID NCT05151471
First seen Jan 09, 2026 · Last updated Apr 30, 2026 · Updated 12 times
Summary
This study looked at whether taking oral edaravone in two different dosing schedules can help slow the worsening of ALS, a nerve disease that weakens muscles over time. About 200 people who had already been in an earlier edaravone study took the drug for up to 48 more weeks. The goal was to see how long it took for their physical function to drop by a certain amount or for death to occur.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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CHU de Quebec-Hopital-Enfant-Jesus
Québec, Quebec, G1J 1Z4, Canada
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Chefarzt Muskelzentrum/ALS Clinic Kantonsspital St.Gallen Muskelzentrum/ALS Clinic
Sankt Gallen, 9007, Switzerland
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Emory University - School of Medicine
Atlanta, Georgia, 30317-2819, United States
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Fukushima Medical University Hospital
Fukushima, Fukushima, 960-1295, Japan
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Hanyang University Medical Center
Wangsimni-ro, Seongdong-gu, 04763, South Korea
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Health Science Center Mcmaster University
Hamilton, Ontario, L8P 1H1, Canada
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Hiroshima University Hospital
Hiroshima, Hiroshima, 734-8551, Japan
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Johns Hopkins University
Baltimore, Maryland, 21205, United States
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Kagawa University Hospital
Kita-gun, Kagawa-ken, 761-0793, Japan
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Kansai Electric Power Hospital
Osaka, Osaka, 553-0003, Japan
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London Health Sciences Centre - University Hospital
London, Ontario, N6A 5A5, Canada
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Murakami Karindoh Hospital
Fukuoka, Fukuoka, 819-8585, Japan
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Nagoya University Hospital
Nagoya, Aichi-ken, 466-8560, Japan
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National Hospital Organization Chibahigashi National Hospital
Chiba, Chiba, 260-8712, Japan
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National Hospital Organization Higashinagoya National Hospital
Nagoya, Aichi-ken, 465-8620, Japan
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National Hospital Organization Iou National Hospital
Kanazawa, Ishikawa-ken, 920-0192, Japan
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National Hospital Organization Kumamoto Saishun Medical Center
Kōshi, Kumamoto, 861-1196, Japan
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National Hospital Organization Osaka Toneyama Medical Center
Toyonaka, Osaka, 560-8552, Japan
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National Hospital Organization Shizuoka Institute of Epilepsy and Neurological Disorders
Shizuoka, Shizuoka, 420-8688, Japan
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National Hospital Organization Utano National Hospital
Kyoto, Kyoto, 616-8255, Japan
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Nerve And Muscle Center Of Texas
Houston, Texas, 77019, United States
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Neurology Associates, P.C - Lincoln
Lincoln, Nebraska, 68506, United States
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Niigata University Medical & Dental Hospital
Niigata, Niigata, 951-8520, Japan
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Northwestern University Feinberg School of Medicine
Chicago, Illinois, 60611-2605, United States
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Saitama Neuropsychiatric Institute
Saitama, 338-8577, Japan
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Teikyo University Hospital
Itabashi-ku, Tokyo, 173-8606, Japan
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Toho University Omori Medical Center
Ōta-ku, Tokyo, 143-8541, Japan
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Tohoku University Hospital
Sendai, Miyagi, 980-8574, Japan
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Tokyo Metropolitan Neurological Hospital
Fuchū, Tokyo, 183-0042, Japan
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UF Health Cancer Center/Clinical Trials Office
Gainesville, Florida, 32610-3633, United States
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Universitaetsklinikum Wuerzburg
Würzburg, 97080, Germany
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University Of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, 15213, United States
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University of Alberta - Walter C Mackenzie Health Sciences Centre (WCM)
Edmonton, Alberta, T6G 2B7, Canada
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University of Washington Medical Center
Seattle, Washington, 98195, United States
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West Virginia University School of Medicine (WVUSoM) - Movement Disorder Clinic
Morgantown, West Virginia, 26506-9180, United States
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Woodland Research Northwest, LLC
Rogers, Arkansas, 72758, United States
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Yokohama City University Hospital
Yokohama, Kanagawa, 236-0004, Japan
Conditions
Explore the condition pages connected to this study.