Early ALS drug trial halted: safety first in fight against nerve disease

NCT ID NCT06215755

Summary

This early-stage study aimed to test the safety and side effects of an experimental drug called VRG50635 in people with ALS (Lou Gehrig's disease). It involved 54 adults with ALS to see how their bodies handled increasing doses of the drug over time and to look for early signs it might help slow the disease. The trial was terminated, meaning it was stopped early, which is common in early-phase studies focused primarily on safety.

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Contacts and locations

Locations

  • Helsinki University Hospital

    Helsinki, Uusimaa, FI-00029, Finland

  • Stan Cassidy Centre for Rehabilitation (Horizon NB)

    Montreal, Quebec, H3A 2B4, Canada

  • The Neuro - Montréal Neurological Institute-Hospital

    Montreal, Quebec, H3A 2B4, Canada

  • Turku University Hospital

    Turku, Western Finland, FI-20520, Finland

  • UZ Leuven

    Leuven, Flemish Brabant, Belgium

  • University Medical Center Utrecht

    Utrecht, 3584 CX, Netherlands

  • University of Eastern Finland, Brain Research Unit

    Kuopio, Eastern Finland, FI-70210, Finland

Conditions

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