Can MCI-186 slow ALS? phase 3 trial results revealed

NCT ID NCT01492686

First seen Jan 07, 2026 · Last updated May 05, 2026 · Updated 19 times

Summary

This study tested a drug called MCI-186 in 137 people with ALS, a nerve disease that weakens muscles over time. Participants received daily IV infusions of the drug or a placebo for 24 weeks. The goal was to see if MCI-186 could slow the disease's progression, measured by a scale that tracks daily function. The trial was completed and compared changes between the drug and placebo groups.

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Contacts and locations

Locations

  • Study site

    Osaka, Japan

Conditions

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