New Two-Drug attack on ALS brain inflammation begins human testing

NCT ID NCT07321860

Summary

This study is testing whether combining two drugs, galunisertib and nerandomilast, can slow the progression of ALS in patients who have a specific biomarker called GREM2. The drugs aim to reduce harmful inflammation and scarring in the nervous system. The trial will enroll 60 adults with relatively recent ALS diagnoses to see if the treatment changes disease-related biomarkers and is safe.

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