Scientists track rare immune disease to unlock its secrets

NCT ID NCT00001350

First seen Jun 24, 2026 · Last updated Jul 01, 2026 · Updated 3 times

Summary

This study follows people with autoimmune lymphoproliferative syndrome (ALPS) and their relatives over many years. Researchers will collect blood and tissue samples, track symptoms, and study genetics to better understand why the immune system attacks the body. The goal is to learn how the disease develops and find better ways to manage it.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could lead to a better understanding of ALPS and point toward targeted treatments for this rare immune disorder.

What could go wrong

This is an observational study, not a treatment trial. It may not directly lead to new therapies, and results may take many years to translate into clinical practice.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

autoimmune disease autoimmune lymphoproliferative syndrome autoimmune lymphoproliferative syndrome type 4 Autoimmune Lymphoproliferative Syndrome, Type IA lymphoproliferative syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••