Race to slow kidney failure in rare genetic disease
NCT ID NCT02855268
Summary
This study tested whether a weekly injection called lademirsen could safely slow the decline of kidney function in adults with Alport syndrome, a genetic condition that damages the kidneys. It involved 43 participants who received either the drug or a placebo for nearly a year. The main goal was to see if the treatment could protect kidney function better than a placebo, but the trial was stopped early.
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Contacts and locations
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Locations
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Columbia University Medical Center_Investigational Site Number :8400004
New York, New York, 10032, United States
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Investigational Site Number :0360001
Parkville, Victoria, 3050, Australia
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Investigational Site Number :0360002
Nedlands, Western Australia, 6009, Australia
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Investigational Site Number :0360003
Herston, Queensland, 4029, Australia
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Investigational Site Number :1560001
Beijing, 100034, China
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Investigational Site Number :1560002
Beijing, 100730, China
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Investigational Site Number :1560004
Guangzhou, 510080, China
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Investigational Site Number :2500001
Paris, 75015, France
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Investigational Site Number :2500002
Toulouse, 31403, France
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Investigational Site Number :7240001
Barcelona, Barcelona [Barcelona], 08025, Spain
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Investigational Site Number :7240002
Madrid / Madrid, Madrid, Comunidad de, 28040, Spain
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Investigational Site Number :7240003
Granada, 18014, Spain
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Investigational Site Number :7240004
Barcelona, Barcelona [Barcelona], 08035, Spain
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Investigational Site Number :7240005
Córdoba, Andalusia, 14004, Spain
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Investigational Site Number :8260001
London, London, City of, NW3 2QG, United Kingdom
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Investigational Site Number :8260002
Nottingham, Nottinghamshire, NG5 1PB, United Kingdom
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Investigational Site Number :8260003
Newcastle upon Tyne, NE7 7DN, United Kingdom
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Investigational Site Number :8400002
Los Angeles, California, 90024, United States
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The Cleveland Clinic Foundation_Investigational Site Number :8400001
Cleveland, Ohio, 44195, United States
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Uniklinik Köln, Innere Medizin II - Nephrologie, Rheumatologie, Diabetologie und Allgemeine Innere Medizin_Investigational Site Number :2760001
Cologne, 50937, Germany
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University of Minnesota Childrens' Hospital_Investigational Site Number :8400003
Minneapolis, Minnesota, 55454, United States
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University of Utah_Investigational Site Number :8400005
Salt Lake City, Utah, 84132, United States
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Universitätsmedizin Göttingen, Klinik für Nephrologie und Rheumatologie_Investigational Site Number :2760002
Göttingen, 37075, Germany
Conditions
Explore the condition pages connected to this study.