New PET tracer aims to spot Parkinson's protein in living brains

NCT ID NCT06891703

First seen Nov 19, 2025 · Last updated May 09, 2026 · Updated 23 times

Summary

This early-phase study tests whether a new radioactive tracer called [18F]ACI-15916 can safely and reliably detect harmful alpha-synuclein protein clumps in the brain using PET scans. About 46 people—including healthy volunteers and those with suspected Parkinson's disease, multiple system atrophy, or Lewy body dementia—will receive the tracer and undergo brain imaging. The goal is to improve diagnosis and understanding of these diseases, not to treat them.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Karolinska Institutet

    RECRUITING

    Solna, Sweden

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.