Antioxidant supplement may boost IVF outcomes for older women

NCT ID NCT07685431

First seen Jul 06, 2026 · Last updated Jul 08, 2026 · Updated 2 times

Summary

This study tests whether taking alpha-lipoic acid (ALA), a powerful antioxidant, for two months before IVF can improve egg quality and pregnancy rates in women aged 35-45 with infertility. Researchers will compare 30 women who take ALA with 30 who do not, measuring embryo quality, mitochondrial function in egg-supporting cells, and clinical pregnancy and live birth rates. The goal is to see if this simple supplement can counteract age-related fertility decline.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Alpha-lipoic acid (ALA), an antioxidant supplement
What this could lead to
If it works, this could point toward a simple supplement to improve egg quality and IVF success in older women.
What could go wrong
This is a small, early study with only 60 participants. The supplement may not improve pregnancy or live birth rates, and results may not apply to all women.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Kaohsiung Veterans General Hospital

    RECRUITING

    Kaohsiung City, 813, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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