Scientists hunt for early warning signs in rare lung disease
NCT ID NCT05297812
First seen Jan 18, 2026 · Last updated Apr 11, 2026 · Updated 11 times
Summary
This study aims to understand why some people with Alpha-1 antitrypsin deficiency, a genetic lung and liver disease, get worse quickly while others stay stable. Researchers will follow 286 patients for three years, using CT scans and blood tests to look for early signs that predict rapid lung decline. The goal is to find better markers for future drug trials, as current lung function tests don't always show disease progression.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Boston University
Boston, Massachusetts, 02118, United States
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Columbia University
New York, New York, 10032, United States
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Medical University of South Carolina
Charleston, South Carolina, 29425, United States
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National Jewish Health
Denver, Colorado, 80206, United States
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University of Alabama at Birmingham
Birmingham, Alabama, 35233, United States
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University of California - Los Angeles
Los Angeles, California, 90095, United States
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University of Chicago
Chicago, Illinois, 60637, United States
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University of North Carolina
Chapel Hill, North Carolina, 27514, United States
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University of Utah
Salt Lake City, Utah, 84108, United States
Conditions
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