Scientists hunt for early warning signs in rare genetic lung disease

NCT ID NCT05297812

Summary

This study aims to find early signs that predict which people with Alpha-1 antitrypsin deficiency, a genetic disease that can damage the lungs and liver, will get worse quickly. Researchers are following 286 adults with the disease for three years, using CT scans and blood tests to track changes. The goal is to discover markers that can help identify high-risk patients earlier, so future treatments can be tested sooner.

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Contacts and locations

Locations

  • Boston University

    Boston, Massachusetts, 02118, United States

  • Columbia University

    New York, New York, 10032, United States

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

  • National Jewish Health

    Denver, Colorado, 80206, United States

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35233, United States

  • University of California - Los Angeles

    Los Angeles, California, 90095, United States

  • University of Chicago

    Chicago, Illinois, 60637, United States

  • University of North Carolina

    Chapel Hill, North Carolina, 27514, United States

  • University of Utah

    Salt Lake City, Utah, 84108, United States

Conditions

Explore the condition pages connected to this study.