New drug combo shrinks lung tumors before surgery in early trial

NCT ID NCT06300424

First seen May 06, 2026 ยท Last updated May 06, 2026

Summary

This study tests a two-step treatment for people with a specific type of lung cancer (EGFR-mutant, stages II to IIIB). First, patients take a targeted pill (almonertinib), then receive a combination of immunotherapy (adebrelimab) and chemotherapy. After that, they have surgery to remove the tumor. The goal is to see if this approach can shrink or eliminate the cancer before surgery. The study includes 32 adults and is currently active but not recruiting.

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Contacts and locations

Locations

  • Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences

    Guangzhou, Guangdong, 510080, China

Conditions

Explore the condition pages connected to this study.