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New drug ALE.P02 targets tough cancers in early trial

NCT ID NCT06747585

Recruiting now Disease control Sponsor: Alentis Therapeutics AG Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 30, 2026 · Updated 2 times

Summary

This study tests a new drug called ALE.P02 in people with advanced squamous cell cancers of the lung, head and neck, cervix, or esophagus that have spread or cannot be removed. The goal is to find the safest and most effective dose and see if it can shrink tumors. About 170 adults will take part in this early-phase trial.

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Conditions

The condition(s) this trial relates to.

cervical squamous cell carcinoma esophageal squamous cell carcinoma head and neck squamous cell carcinoma non-small cell squamous lung carcinoma Squamous Cell Carcinoma of Head and Neck

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CERVICAL SQUAMOUS CELL CARCINOMA ESOPHAGEAL SQUAMOUS CELL CARCINOMA HEAD AND NECK SQUAMOUS CELL CARCINOMA SQUAMOUS NON-SMALL CELL LUNG CANCER

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • AP-HM Hôpital de La Timone CEPCM

    RECRUITING

    Marseille, 13005, France

  • Asan Medical Center - Oncology

    RECRUITING

    Seoul, 5505, South Korea

  • Buddihist Tzu Chi Medical Foundation - Taipei Tzu Chi Hospital

    RECRUITING

    Taipei, 231020, Taiwan

  • CHRU De Lille- Hôpital Claude Huriez - Medical Oncology

    RECRUITING

    Lille, 59000, France

  • Centre Georges Francois Leclerc - Oncologie Medicale

    RECRUITING

    Dijon, 21079, France

  • Centre Hospitalier Universitaire (CHU) de Toulouse - IUCT Oncopole

    RECRUITING

    Toulouse, 31100, France

  • Centro Ricerche Cliniche Verona

    RECRUITING

    Verona, Italy

  • Changhua Christian Medical Foundation Changhua Christian Hospital

    RECRUITING

    Changhua, 50006, Taiwan

  • Changhua Christian Medical Foundation Changhua Christian Hospital

    RECRUITING

    Changhua, 500209, Taiwan

  • Chinese University of Hong Kong - Prince of Wales Hospital

    RECRUITING

    Shatin, N.T., Hong Kong

  • Hackensack University Medical Center

    RECRUITING

    Hackensack, New Jersey, 07601, United States

  • Hospital Universitari Vall D Hebron

    RECRUITING

    Barcelona, 08035, Spain

  • Hospital Universitario 12 de Octubre

    RECRUITING

    Madrid, 28041, Spain

  • Hospital Universitario Quironsalud Madrid

    RECRUITING

    Pozuelo de Alarcón, Madrid, 28223, Spain

  • Hospital Universitario Virgen De La Macarena

    RECRUITING

    Seville, 41009, Spain

  • Hospital Universitario Virgen De La Victoria

    RECRUITING

    Málaga, 29010, Spain

  • Hospital Universitario Y Politécnico La Fe

    RECRUITING

    Valencia, 46026, Spain

  • IEO - Istituto Europeo di Oncologia, IRCCS

    RECRUITING

    Milan, 20141, Italy

  • Institut Bergonie

    RECRUITING

    Bordeaux, 33000, France

  • Institut Gustave Roussy

    RECRUITING

    Villejuif, 94800, France

  • Istituto Clinico Humanitas

    RECRUITING

    Milan, 20089, Italy

  • Istituto Nazionale del Tumori, Fondazione IRCCS

    RECRUITING

    Milan, 20133, Italy

  • Mayo Foundation for Medical Education and Research - Mayo Cl

    RECRUITING

    Scottsdale, Arizona, 85259, United States

  • NEXT Oncology Barcelona

    RECRUITING

    Barcelona, 08023, Spain

  • NEXT Oncology Virginia

    RECRUITING

    Fairfax, Virginia, 22031, United States

  • National Cancer Center

    RECRUITING

    Goyang-si, 10408, South Korea

  • National Cancer Centre Singapore

    RECRUITING

    Singapore, South West, 168583, Singapore

  • National Taiwan University Hospital

    RECRUITING

    Taipei, 100225, Taiwan

  • National University Cancer Institue

    RECRUITING

    Singapore, South West, 11907, Singapore

  • Norton Cancer Institue Downtown

    RECRUITING

    Louisville, Kentucky, 40202, United States

  • Ospedale San Raffaele, IRCCS

    RECRUITING

    Milan, 20132, Italy

  • Ospedale Santa Maria delle Croci di Ravenna Oncologia

    RECRUITING

    Ravenna, 48121, Italy

  • PU A. Gemelli, Universita Cattolica del Sacro Cuore

    RECRUITING

    Roma, Italy

  • Providence Medical Foundation

    RECRUITING

    Fullerton, California, 92835, United States

  • START Hospital HM Nou Delfos

    RECRUITING

    Barcelona, Spain

  • START Madrid- Centro Integral Oncologico Clara Campal

    RECRUITING

    PAU de Sanchinarro, Madrid, 28050, Spain

  • Seoul National University Hospital

    RECRUITING

    Seoul, 03080, South Korea

  • Severance Hospital, Yonsei University Health System

    RECRUITING

    Seoul, 03722, South Korea

  • The University of Chicago Medical Center - Oncology

    RECRUITING

    Chicago, Illinois, 60637, United States

  • USC Norris Comprehensive Cancer Center

    RECRUITING

    Los Angeles, California, 90033, United States

  • Yale Comprehensive Cancer Center

    RECRUITING

    New Haven, Connecticut, 06510, United States

More trials for these conditions

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