New scan could spot hidden tumors behind rare bone disease

NCT ID NCT07366099

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new type of PET/CT scan using a tracer called Al18F-NOTA-LM3 to find tumors that cause tumor-induced osteomalacia (TIO), a rare condition where bones soften and weaken. Researchers will compare this new scan to the standard 68Ga-DOTATATE PET/CT in 40 adults with suspected or confirmed TIO. The goal is to see if the new method is more sensitive and specific at locating these tumors.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Al18F-NOTA-LM3 (a radioactive tracer for PET/CT scans)
What this could lead to
If successful, this could provide a more accurate way to detect the tumors causing osteomalacia, leading to earlier treatment and better outcomes.
What could go wrong
This is a small pilot study with only 40 participants, so results may not apply to everyone. The new tracer may not prove better than existing methods.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for TUMOR-INDUCED OSTEOMALACIA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Peking Union Medical College Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100730, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••