New drug trial aims to slow Alzheimer's progression

NCT ID NCT04592874

Completed Disease control Sponsor: Alector Inc. Source: ClinicalTrials.gov ↗

Summary

This study tested whether an investigational drug called AL002 could slow the progression of early Alzheimer's disease. 356 participants with early-stage Alzheimer's received either the drug or a placebo via intravenous infusion over 96 weeks. Researchers measured changes in memory, thinking, and daily function to see if the treatment helped control the disease.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

AMITA Health Clinical Research Institute

Elk Grove Village, Illinois, 60007, United States
ASST degli Spedali Civili di Brescia - Spedali Civili di Brescia

Brescia, 25123, Italy
ATP Clinical Research

Costa Mesa, California, 92626, United States
Abington Neurologic Associates

Abington, Pennsylvania, 19090, United States
Advanced Clinical Institute

Neptune City, New Jersey, 07753, United States
Alzheimers Research and Treatment Center

Wellington, Florida, 33449, United States
Axiom Clinical Research FL

Tampa, Florida, 33609, United States
Azienda Ospedaliero Universitaria Pisana

Pisa, 56126, Italy
Azienda Policlinico Umberto I

Rome, Lazio, 00185, Italy
Banner Alzheimer's Institute

Phoenix, Arizona, 85006, United States
Baycrest Health Sciences

Toronto, Ontario, Ontario, Canada
Boston Center for Memory

Newton, Massachusetts, 02459, United States
Box Hill Hospital

Box Hill, Victoria, 3128, Australia
Brain Matters Research - ERG

Delray Beach, Florida, 33445, United States
Brain Research Center Amsterdam

Amsterdam, 1081 GN, Netherlands
Brain Research Center Den Bosch

's-Hertogenbosch, North Brabant, 5223 GV, Netherlands
Bruyère Research Institute

Ottawa, Ontario, K1N 5C8, Canada
CGM Research Trust

Christchurch, 8083, New Zealand
Centre Hospitalier Universitaire de Toulouse

Toulouse, 31059, France
Centro de Atencion Especializada Oroitu

Getxo, Basque Country, 48993, Spain
Centro de Psiquiatría Biológica Instituto Senecta

Mendoza, 5500, Argentina
Centrum Medyczne NeuroProtect

Warsaw, Masovian Voivodeship, 01-684, Poland
Charite Campus Buch

Berlin, 13125, Germany
Charité - Universitätsmedizin Berlin (CBF)

Berlin, 12203, Germany
Charter Research

Lady Lake, Florida, 32159, United States
ClinCloud, LLC

Maitland, Florida, 32751, United States
Clinical Trial Network

Houston, Texas, 77074-2085, United States
Columbia University College of Physicians and Surgeons

New York, New York, 10032-3725, United States
Conquest Clinical Research (Winter Park)

Winter Park, Florida, 32789, United States
EUROMEDIS Sp. z o.o.

Szczecin, West Pomeranian Voivodeship, 70-111, Poland
Emory University

Atlanta, Georgia, 30322, United States
Feinstein Institute For MR

Manhasset, New York, 11030, United States
Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico

Milan, 20122, Italy
Fondazione IRCCS Di Rilievo Nazionale Istituto Nazionale Neurologico Carlo Besta

Milan, 20133, Italy
Fondazione Policlinico Universitario A Gemelli

Rome, Lazio, 00168, Italy
Fundacion ACE Instituto Catalan de Neurociencias

Barcelona, 08028, Spain
Fundacion CITA Alzheimer Fundazioa

Donostia / San Sebastian, Guipuzcoa, 20009, Spain
Georgetown University Medical Center

Washington D.C., District of Columbia, 20007, United States
Gerontopole

Toulouse, 31059, France
Glasgow Memory Clinic

Motherwell, ML1 4UF, United Kingdom
Greater Manchester Mental Health NHS Foundation Trust

Manchester, M8 5RB, United Kingdom
Hattiesburg Clinic

Hattiesburg, Mississippi, 39401, United States
Hopital Lariboisiere

Paris, 75010, France
Hospital Clinic de Barcelona

Barcelona, 08036, Spain
Hospital Universitari i Politecnic La Fe de Valencia

Valencia, 46026, Spain
Hospital Universitario Doctor Peset

Valencia, 46017, Spain
Hospital Universitario Ramon y Cajal

Madrid, 28034, Spain
Hospital Viamed Montecanal

Zaragoza, 50012, Spain
Hospital de La Santa Creu i Sant Pau

Barcelona, Catalonia, 08041, Spain
Hôpital Roger Salengro

Lille, Nord, 59037, France
Hôpital de la Pitié Salpétrière

Paris, 75013, France
IRCCS - Centro S. Giovanni di Dio Fatebenefratelli

Brescia, Lombardy, 25125, Italy
Instituto Kremer

Córdoba, X5004AOA, Argentina
K2 Medical Research

Maitland, Florida, 32751, United States
K2 The Villages

The Villages, Florida, 32159, United States
K2 Winter Garden Ocoee

Ocoee, Florida, 34761, United States
KaRa Institute of Neurological Disease

Macquarie Park, New South Wales, 2113, Australia
Kawartha Regional Memory Clinic

Peterborough, Ontario, K9H 2P4, Canada
Klinikum rechts der Isa der Technischen Universitaet Muenchen

München, 81675, Germany
LMU Klinikum der Universität München

München, 81377, Germany
NZOZ Wroclawskie Centrum Alzheimerowskie

Wroclaw, Lower Silesian Voivodeship, 53-110, Poland
Okanagan Clinical Trials

Kelowna, British Columbia, V1Y 1Z9, Canada
Ospedale Civile di Baggiovara

Modena, 41126, Italy
Ospedale S Giovanni Calibita Fatebenefratelli

Rome, Lazio, 00186, Italy
Ospedale degli Infermi

Ponderano, 13875, Italy
Parkwood Institute

London, Ontario, N6C 0A7, Canada
Progressive Medical Research

Port Orange, Florida, 32127-5170, United States
Re: Cognition Health - Guildford

Guildford, Surrey, GU2 7YD, United Kingdom
Re:Cognition Health Bristol

Bristol, BS32 4SY, United Kingdom
Re:Cognition Health London

London, W1G 9JF, United Kingdom
Re:Cognition Health Plymouth

Plymouth, Pl6 8BT, United Kingdom
SMarT Minds WA

Nedlands, Western Australia, 6009, Australia
SOMED CR

Warsaw, 01-737, Poland
SUNY Upstate Medical Center

Syracuse, New York, 13210, United States
South Florida Neurology Associates

Boca Raton, Florida, 33487, United States
Summit Research Network

Portland, Oregon, 97210, United States
The Alfred Hospital

Parkville, Victoria, 3050, Australia
The National Hospital for Neurology and Neurosurgery

London, WC1N 3BG, United Kingdom
Toronto Memory Clinic

Toronto, Ontario, M3B 2S7, Canada
True North Clinical Research - Halifax

Halifax, Nova Scotia, B3S 1N2, Canada
True North Clinical Research - New Minas

New Minas, Nova Scotia, B4N 3R7, Canada
University Clinic Heidelberg

Mannheim, 68159, Germany
University of Cincinnati MC

Cincinnati, Ohio, 45219, United States
University of Kentucky

Lexington, Kentucky, 40536, United States
University of Rochester Medical Center

Rochester, New York, 14620, United States
Universitätsklinikum Ulm

Ulm, 89081, Germany
Woodlands Research Network, LLC - ERG

Rogers, Arkansas, 72758, United States

Conditions

Explore the condition pages connected to this study.

ALZHEIMER DISEASE