New antibody trial aims to help patients with rare, deadly organ disease live longer

NCT ID NCT04504825

Ongoing Disease control Sponsor: Alexion Pharmaceuticals, Inc. Source: ClinicalTrials.gov ↗

Summary

This study is testing whether adding an experimental antibody called CAEL-101 to standard treatment helps people with advanced AL amyloidosis. AL amyloidosis is a rare disease where abnormal proteins build up in organs like the heart, causing serious damage. The research will see if CAEL-101 helps patients live longer and reduces hospital visits for heart problems compared to standard treatment alone.

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Contacts and locations

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Locations

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Duarte, California, 91010, United States
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Palo Alto, California, 94304, United States
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San Francisco, California, 94143, United States
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Weston, Florida, 33331, United States
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Indianapolis, Indiana, 46202, United States
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New Orleans, Louisiana, 70112, United States
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Boston, Massachusetts, 02111, United States
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Boston, Massachusetts, 02118, United States
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Boston, Massachusetts, 02215, United States
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Detroit, Michigan, 48201, United States
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Rochester, Minnesota, 55905, United States
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St Louis, Missouri, 63110, United States
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New York, New York, 10032, United States
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New York, New York, 10065, United States
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Rochester, New York, 14642, United States
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Winston-Salem, North Carolina, 27157, United States
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Cleveland, Ohio, 44195, United States
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Columbus, Ohio, 43210, United States
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Portland, Oregon, 97239, United States
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Philadelphia, Pennsylvania, 19104, United States
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Nashville, Tennessee, 37232, United States
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Dallas, Texas, 75390, United States
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Houston, Texas, 77030, United States
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Salt Lake City, Utah, 84112, United States
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Seattle, Washington, 98109, United States
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Milwaukee, Wisconsin, 53226, United States
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Box Hill, 3128, Australia
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Brisbane, 4102, Australia
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Westmead, 2145, Australia
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Linz, 4020, Austria
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Vienna, 1090, Austria
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Anderlecht, 1070, Belgium
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Leuven, 3000, Belgium
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Porto Alegre, 90110-270, Brazil
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Ribeirão Preto, 14048-900, Brazil
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Salvador, 41253-190, Brazil
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São José do Rio Preto, 15090-000, Brazil
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Calgary, Alberta, T2N 4N2, Canada
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Edmonton, Alberta, T6G 1Z2, Canada
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Toronto, Ontario, M5G 2M9, Canada
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Beijing, 100730, China
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Guangzhou, 510180, China
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Hangzhou, 310009, China
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Wenzhou, 325000, China
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Wuhan, 430022, China
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Ostrava - Poruba, 70852, Czechia
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Prague, 12808, Czechia
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Caen, 14033, France
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Créteil, 94000, France
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Limoges, 87042, France
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Marseille, 13009, France
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Paris, 75010, France
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Pessac, 33604, France
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Pierre-Bénite, 69310, France
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Poitiers, 86021, France
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Rennes, 35033, France
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Toulouse, 31100, France
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Tours, 37044, France
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Berlin, 13353, Germany
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Düsseldorf, 40225, Germany
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Essen, 45147, Germany
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Hamburg, 22767, Germany
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Heidelberg, 69120, Germany
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Würzburg, 97080, Germany
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Athens, 11528, Greece
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Rio, 26504, Greece
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Haifa, 31096, Israel
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Jerusalem, 91120, Israel
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Tel Litwinsky, 52621, Israel
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Napoli, 80131, Italy
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Pavia, 27100, Italy
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Pisa, 56126, Italy
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Roma, 00128, Italy
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Fukushima, 960-1295, Japan
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Nagoya, 467-8602, Japan
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Shibuya-ku, 150-8935, Japan
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Groningen, 9713 GZ, Netherlands
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Utrecht, 3508 GA, Netherlands
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Gdansk, 80-214, Poland
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Poznan, 60-569, Poland
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Warsaw, 01-748, Poland
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Seoul, 03080, South Korea
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Seoul, 06351, South Korea
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Barcelona, 08036, Spain
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Barcelona, 8035, Spain
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Gijón, 33394, Spain
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Majadahonda, 28222, Spain
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Pamplona, 31008, Spain
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Seville, 41013, Spain
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London, WC1E 6AG, United Kingdom

Conditions

Explore the condition pages connected to this study.

AL AMYLOIDOSIS