Can AI read skin biopsies as well as expert pathologists?

NCT ID NCT07787481

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Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
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Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

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Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 26, 2026 · Last updated Aug 27, 2026 · Updated 1 time

Summary

This study asks whether an artificial intelligence algorithm can accurately diagnose seborrheic keratosis—a common, non-cancerous skin growth—from tissue samples. Researchers will compare the AI's performance against certified dermatopathologists using 30 preserved slides. The goal is to see if AI can match human expertise in identifying this condition, which could eventually support faster and more consistent diagnoses.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could support the use of AI as a reliable aid for pathologists, potentially speeding up and standardizing skin lesion diagnosis.
What could go wrong
The study is small and early, and AI performance on a limited set of slides may not reflect real-world accuracy across diverse cases or labs.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2026

An estimate. Start dates often move.

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Seborrheic keratosis H\&E stained glass slides from the pathology archive of Al-hussein dermatopathology unit.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Histopathological slides diagnosed as Seborrheic keratosis. 2. Slides with adequate staining and preservation allowing clear visualization of histopathological features. Exclusion Criteria: 1. Slides with poor staining quality or significant artifacts interfering with histopathological interpretation. 2. Slides that were damaged, faded, or inadequately preserved. 3. Cases with uncertain or inconclusive original diagnoses. 4. Slides that could not be successfully digitized due to technical limitations ex: very short or too long slides.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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  3. A doctor treating you

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Contacts and locations

Locations

  • Faculty of medicine, Al-Azhar University boys branch in Cairo

    Cairo, Egypt

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