AI could spot heart transplant rejection without a biopsy

NCT ID NCT06178744

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study at Mayo Clinic is testing whether an artificial intelligence (AI) program can detect heart transplant rejection using standard tests like ECG and ultrasound. Researchers will enroll 500 heart transplant patients and compare the AI's findings to biopsy results. If it works, this approach could make rejection monitoring faster and less invasive.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Artificial intelligence algorithm analyzing ECG and cardiac ultrasound images

What this could lead to

If successful, this AI could help doctors detect heart transplant rejection earlier and more accurately, potentially reducing the need for invasive biopsies.

What could go wrong

This is an early-stage study focused on diagnostic accuracy, not treatment. The AI may not perform well enough in real-world settings, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CARDIAC TRANSPLANT REJECTION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

transplant rejection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mayo Clinic in Rochester

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••