AI reads chest X-Rays to predict lung cancer risk

NCT ID NCT05817110

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing an artificial intelligence (AI) program called qXR that analyzes chest X-rays to give a lung nodule malignancy score — a number that indicates how likely a lung nodule is to be cancer. Researchers will compare the AI's score to the results of CT scans and radiologist reviews in about 712 adults aged 35 and older who have a lung nodule found on X-ray. The goal is to see if the AI can reliably tell high-risk from low-risk nodules, which could help doctors decide who needs a CT scan and who can safely wait.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

AI software (qXR) that analyzes chest X-rays to give a lung nodule malignancy score

What this could lead to

If successful, this AI tool could help doctors quickly identify which lung nodules need further testing, potentially catching lung cancer earlier and reducing unnecessary CT scans.

What could go wrong

This is an observational study, not a treatment trial. The AI may not be accurate enough in real-world settings, and results may not apply to all populations or healthcare systems.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

lung cancer lung carcinoma lung neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Research Site

    Alexandria, Egypt

  • Research Site

    Cairo, Egypt

  • Research Site

    Gurugram, Haryana, 122001, India

  • Research Site

    New Delhi, National Capital Territory of Delhi, 110005, India

  • Research Site

    New Delhi, National Capital Territory of Delhi, 110017, India

  • Research Site

    New Delhi, National Capital Territory of Delhi, 201012, India

  • Research Site

    Hyderabad, Telangana, 500003, India

  • Research Site

    Bangalore, 560011, India

  • Research Site

    Bangalore, 560038, India

  • Research Site

    Chennai, 600026, India

  • Research Site

    Chennai, 600040, India

  • Research Site

    Chennai, 600045, India

  • Research Site

    Chennai, 600053, India

  • Research Site

    Chennai, 600116, India

  • Research Site

    Kolkata, 700025, India

  • Research Site

    Mumbai, 400069, India

  • Research Site

    Pune, 411011, India

  • Research Site

    Surabaya, 60286, Indonesia

  • Research Site

    Monterrey, Nuevo León, 64460, Mexico

  • Research Site

    Mexico City, 6720, Mexico

  • Research Site

    Ankara, Turkey, 06100, Turkey (Türkiye)

  • Research Site

    Mersin, Turkey, 33010, Turkey (Türkiye)