AI reads faces to diagnose rare genetic diseases

NCT ID NCT06219421

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study aims to train an artificial intelligence system to recognize rare genetic diseases by analyzing front and profile facial photographs. Researchers will collect photos from 22,000 patients with craniofacial features linked to rare conditions, as well as control subjects. The goal is to help doctors diagnose these diseases faster and more accurately, especially when subtle facial signs are hard to spot.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could lead to a faster, AI-assisted way to diagnose rare genetic diseases from facial photos, reducing years-long delays.
What could go wrong
This is an early-stage observational study, not a treatment trial. The AI may not work equally well across all ethnicities or rare conditions, and it won't replace genetic testing.

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Conditions

The condition(s) this trial relates to.

body dysmorphic disorder Congenital Abnormalities Rare Diseases

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Necker - Hôpital des Enfants Malades

    RECRUITING

    Paris, France

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Other studies related to the condition(s) this trial covers.