New combo therapy aims to silence hepatitis b virus

NCT ID NCT07069569

First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 29 times

Summary

This study tests whether adding an experimental drug (AHB-137) to either a hepatitis B vaccine or an immune-boosting medicine (pegylated interferon) can help people with chronic hepatitis B stop their daily antiviral pills without the virus coming back. About 127 adults with HBeAg-negative chronic hepatitis B who are already on standard antiviral therapy will take part. The main goal is to see if the virus stays undetectable 24 weeks after all treatments are stopped.

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Contacts and locations

Locations

  • Beijing Friendship Hospital, Capital Medical University

    Beijing, Beijing Municipality, China

Conditions

Explore the condition pages connected to this study.