New drug cocktail shows promise for resistant blood cancer

NCT ID NCT05199051

First seen Jan 09, 2026 · Last updated May 15, 2026 · Updated 21 times

Summary

This study is testing a combination of two drugs, gemtuzumab ozogamicin (GO) and gilteritinib, in adults with a type of acute myeloid leukemia (AML) that has come back or not responded to treatment. The leukemia must have a specific genetic change called FLT3 mutation. The goal is to see if adding gilteritinib to the standard GO-chemotherapy platform is safe and helps patients live longer without the cancer returning. About 19 participants are being treated in this early-phase trial across France.

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Contacts and locations

Locations

  • CHMS de Chambery

    Chambéry, France

  • CHRU Nancy

    Nancy, France

  • CHU Bordeaux

    Bordeaux, France

  • CHU Limoges

    Limoges, France

  • CHU d'Amiens

    Amiens, France

  • CHU d'Angers

    Angers, France

  • CHU de Caen

    Caen, France

  • Centre Henri Becquerel

    Rouen, France

  • Centre Hospitalier Universitaire de Nice

    Nice, France

  • Centre Hospitalier de Versailles

    Versailles, France

  • HIA Percy

    Clamart, France

  • Hôpital Saint Louis

    Paris, France

Conditions

Explore the condition pages connected to this study.