New cancer drug combo enters first human tests

NCT ID NCT05025085

Summary

This early-stage study tested a new drug called AGEN1777, both by itself and combined with an existing immunotherapy drug, in 25 patients with advanced solid tumors that had stopped responding to standard treatments. The main goal was to find a safe dose and understand how the body processes the drug. Researchers also looked for early signs that the treatment might help control the cancer.

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Contacts and locations

Locations

  • Lifespan Cancer Institute

    Providence, Rhode Island, 02903, United States

  • Local Institution - 0001

    Providence, Rhode Island, 02903, United States

  • Local Institution - 024

    Southfield, Michigan, 48075, United States

  • Local Institution - 072

    Cincinnati, Ohio, 45267-0558, United States

  • Local Institution - 164

    Dallas, Texas, 75230, United States

  • Local Institution - 165

    Grand Rapids, Michigan, 49546, United States

  • MD Anderson Cancer Center Thoracic-Head & Neck Med Onc

    Houston, Texas, 77030, United States

  • Mary Crowley Cancer Research

    Dallas, Texas, 75251, United States

  • Providence Cancer Institute

    Portland, Oregon, 97213, United States

  • START Midwest

    Grand Rapids, Michigan, 49546, United States

  • University of Cincinnati Cancer Center

    Cincinnati, Ohio, 45267, United States

Conditions

Explore the condition pages connected to this study.