First pill targets Cancer's genetic engine in brain tumors

NCT ID NCT02481154

Summary

This early-stage study tested a new oral drug, AG-881, in adults with advanced solid tumors, including a type of brain tumor called glioma, that have specific IDH gene mutations. The main goals were to find a safe dose and see how the body processes the drug. Researchers enrolled 95 patients to first test increasing doses and then expand the group at the most promising dose.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

  • MD Anderson Cancer Center

    Houston, Texas, 75390, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Sarah Cannon Research Institute

    Nashville, Tennessee, 37203, United States

  • UCLA Oncology Center

    Los Angeles, California, 90024, United States

  • UT Southwestern Medical Center

    Dallas, Texas, 77030, United States

  • University of California San Francisco

    San Francisco, California, 94143, United States

  • University of Miami

    Miami, Florida, 33136, United States

Conditions

Explore the condition pages connected to this study.