Pacemaker breakthrough could change heart failure care for millions with irregular heartbeat

NCT ID NCT06299514

First seen Feb 02, 2026 · Last updated May 24, 2026 · Updated 18 times

Summary

This study tests if a newer pacemaker method (conduction system pacing) combined with a targeted heart ablation works better than standard medications for controlling heart rate in 600 people with both atrial fibrillation and heart failure. The goal is to reduce deaths, heart failure events, and improve quality of life. Participants will be randomly assigned to either the pacemaker-plus-ablation group or the medication-only group and followed for one year.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centre Hospitalier de L'Université de Montréal (CHUM)

    RECRUITING

    Montreal, Quebec, H2X0A9, Canada

    Contact

  • Hamilton Health Sciences Corporation

    RECRUITING

    Hamilton, Ontario, L8L2X2, Canada

    Contact

  • Hôpital Fleurimont

    RECRUITING

    Sherbrooke, Quebec, J1H5N4, Canada

    Contact

  • Institut universitaire de cardiologie et de pneumologie Québec - Université Laval (IUCPQ-ULaval)

    RECRUITING

    Québec, Quebec, G1V4G5, Canada

    Contact

  • London Health Sciences Centre - University Hospital

    RECRUITING

    London, Ontario, N6A5A5, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Montreal Heart Institute

    RECRUITING

    Montreal, Quebec, Canada

    Contact

  • Nova Scotia Health Authority

    RECRUITING

    Halifax, Nova Scotia, B3S0H6, Canada

    Contact

  • Ottawa Heart Institute Research Corporation

    RECRUITING

    Ottawa, Ontario, K1Y4W7, Canada

    Contact

  • Southlake Regional Health Centre

    RECRUITING

    Newmarket, Ontario, Canada

    Contact

  • Sunnybrook Health Sciences Centre

    NOT_YET_RECRUITING

    Toronto, Ontario, Canada

    Contact

  • Victoria Cardiac Arrhythmia Trials

    NOT_YET_RECRUITING

    Victoria, British Columbia, Canada

    Contact

  • Waterloo Wellington Cardiovascular Research Institute

    RECRUITING

    Kitchener, Ontario, N2G1G3, Canada

    Contact

Conditions

Explore the condition pages connected to this study.