New study tracks safety of adzynma for rare blood clot disorder

NCT ID NCT07353099

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at the real-world safety of Adzynma, a lab-made protein, in people with congenital thrombotic thrombocytopenic purpura (cTTP), a rare inherited blood disorder. Researchers will review medical records of about 50 children and adults to see how many develop allergic reactions or antibodies that stop the drug from working. The goal is to better understand long-term safety and effects during pregnancy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Adzynma (lab-made ADAMTS13 protein)

What this could lead to

If successful, this study will provide crucial safety data on Adzynma, helping doctors better manage cTTP patients.

What could go wrong

This is an observational study, not a trial testing new effects. It only reviews existing medical records, so it cannot prove new benefits or risks beyond what is already known.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for THROMBOTIC THROMBOCYTOPENIC PURPURA (TTP) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

congenital thrombotic thrombocytopenic purpura thrombotic thrombocytopenic purpura

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AKH - Medizinische Universitaet Wien

    RECRUITING

    Vienna, 1090, Austria

    Contact

    Contact Email: •••••@•••••

  • Klinikum Rechts der Isar der Technischen Universitaet Muenchen

    NOT_YET_RECRUITING

    München, 81675, Germany

    Contact

    Contact

  • LMU Klinikum

    NOT_YET_RECRUITING

    München, Germany

    Contact

    Contact Email: •••••@•••••

  • Universitaetsklinikum Jena

    NOT_YET_RECRUITING

    Jena, 7743, Germany

    Contact

    Contact Email: •••••@•••••

  • Universitaetsklinikum Koeln

    NOT_YET_RECRUITING

    Cologne, 50937, Germany

    Contact

    Contact Email: •••••@•••••

  • Universitaetsklinikum Leipzig

    NOT_YET_RECRUITING

    Leipzig, 4103, Germany

    Contact Email: •••••@•••••

    Contact

  • Universitatsklinikum Bonn

    NOT_YET_RECRUITING

    Bonn, 53127, Germany

    Contact

    Contact Email: •••••@•••••