New study tracks safety of adzynma for rare blood clot disorder

NCT ID NCT07353099

Recruiting now Knowledge-focused Sponsor: Takeda Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at the real-world safety of Adzynma, a lab-made protein, in people with congenital thrombotic thrombocytopenic purpura (cTTP), a rare inherited blood disorder. Researchers will review medical records of about 50 children and adults to see how many develop allergic reactions or antibodies that stop the drug from working. The goal is to better understand long-term safety and effects during pregnancy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Adzynma (lab-made ADAMTS13 protein)
What this could lead to: If successful, this study will provide crucial safety data on Adzynma, helping doctors better manage cTTP patients.
What could go wrong: This is an observational study, not a trial testing new effects. It only reviews existing medical records, so it cannot prove new benefits or risks beyond what is already known.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

congenital thrombotic thrombocytopenic purpura thrombotic thrombocytopenic purpura

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

THROMBOTIC THROMBOCYTOPENIC PURPURA (TTP)

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

AKH - Medizinische Universitaet Wien
RECRUITING

Vienna, 1090, Austria
Klinikum Rechts der Isar der Technischen Universitaet Muenchen
NOT_YET_RECRUITING

München, 81675, Germany
LMU Klinikum
NOT_YET_RECRUITING

München, Germany
Universitaetsklinikum Jena
NOT_YET_RECRUITING

Jena, 7743, Germany
Universitaetsklinikum Koeln
NOT_YET_RECRUITING

Cologne, 50937, Germany
Universitaetsklinikum Leipzig
NOT_YET_RECRUITING

Leipzig, 4103, Germany
Universitatsklinikum Bonn
NOT_YET_RECRUITING

Bonn, 53127, Germany

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