New study explores drug cocktails for Hard-to-Treat cancers

NCT ID NCT03851614

First seen Feb 10, 2026 · Last updated May 15, 2026 · Updated 11 times

Summary

This study tests two drug combinations in people with advanced colorectal, pancreatic, or leiomyosarcoma cancers that have not responded to standard treatments. Participants receive either olaparib plus durvalumab or cediranib plus durvalumab. The main goal is to measure changes in genes and immune markers in tumors and blood samples to understand how the body responds.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Princess Margaret Cancer Centre

    Toronto, Ontario, M5G 2M9, Canada

Conditions

Explore the condition pages connected to this study.