New antibody combo aims to control advanced prostate cancer

NCT ID NCT06095089

Recruiting now Disease control Sponsor: Janssen Research & Development, LLC Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 31, 2026 · Updated 3 times

Summary

This early-phase study tests two experimental drugs (JNJ-87189401 and JNJ-78278343) that help the immune system attack prostate cancer cells. The study involves about 355 men with advanced prostate cancer. The main goal is to find the safest dose and check for side effects.

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Conditions

The condition(s) this trial relates to.

prostate cancer prostate carcinoma prostate neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADVANCED PROSTATE CANCER PROSTATIC NEOPLASMS

Contacts and locations

Locations

Centre Leon Berard
RECRUITING

Lyon, 69008, France
Emory University Winship Cancer Institute
RECRUITING

Atlanta, Georgia, 30322, United States
Greenslopes Private Hospital
RECRUITING

Greenslopes, 4120, Australia
Herbert Irving Comprehensive Cancer Center Columbia University Medical Center
RECRUITING

New York, New York, 10032, United States
Institut Bergonie
RECRUITING

Bordeaux, 33000, France
Institut Gustave Roussy
RECRUITING

Villejuif, 94800, France
MD Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States
Oregon Health And Science University
RECRUITING

Portland, Oregon, 97239, United States
Peter MacCallum Cancer Centre
RECRUITING

Melbourne, 3000, Australia
START New Jersey
RECRUITING

East Brunswick, New Jersey, 08816, United States
Sidney Kimmel Cancer Center - Jefferson Health
RECRUITING

Philadelphia, Pennsylvania, 19107, United States
South Texas Accelerated Research Therapeutics, LLC (START)
RECRUITING

San Antonio, Texas, 78229, United States
Swedish Medical Center
RECRUITING

Seattle, Washington, 98104, United States
Tennessee Oncology
RECRUITING

Nashville, Tennessee, 37203, United States
The Cancer Institute Hospital of JFCR
RECRUITING

Tokyo, 135 8550, Japan
The First Affiliated Hospital of Wenzhou Medical University
RECRUITING

Wenzhou, 325000, China
University Of Minnesota
RECRUITING

Minneapolis, Minnesota, 55455, United States
University of Colorado Anschutz Medical Campus
RECRUITING

Aurora, Colorado, 80045, United States

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