New combo therapy shows promise in taming tough pancreatic cancer

NCT ID NCT04257448

First seen Sep 30, 2025 · Last updated May 15, 2026 · Updated 29 times

Summary

This study tested a sequence of drugs to control advanced pancreatic cancer that has spread. 75 patients received an initial combination of chemotherapy plus drugs that modify gene activity and boost the immune system. Those whose disease was controlled then received additional immune-targeting therapy. The goal was to find a safe and effective way to manage this aggressive cancer.

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Contacts and locations

Locations

  • Klinikum Nürnberg

    Nuremberg, 90419, Germany

  • Ludwig-Maximilians-Universität München

    München, 81377, Germany

  • Uniklinik Köln

    Cologne, 50937, Germany

  • Universitätsklinikum Essen

    Essen, 45147, Germany

  • Universitätsklinikum Frankfurt

    Frankfurt, 60590, Germany

  • Universitätsklinikum Hamburg-Eppendorf

    Hamburg, 20251, Germany

  • Universitätsklinikum Ulm

    Ulm, 89081, Germany

  • Universitätsklinikum Würzburg

    Würzburg, 97080, Germany

  • Universitätsmedizin Göttingen

    Göttingen, 37075, Germany

Conditions

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