New hope for Tough-to-Treat throat cancer: three drugs vs. two

NCT ID NCT05904080

Recruiting now Disease control Sponsor: National Cancer Institute (NCI) Source: ClinicalTrials.gov ↗

Summary

This study is for people with advanced nasopharyngeal cancer (a type of throat cancer) that has spread or returned after standard treatments. It will test if adding a pill called cabozantinib to two immunotherapy drugs (nivolumab and ipilimumab) works better than the two immunotherapies alone. The goal is to see if the three-drug combination can better control the cancer's growth and help patients live longer without their disease getting worse.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Benefis Sletten Cancer Institute
RECRUITING

Great Falls, Montana, 59405, United States

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Billings Clinic Cancer Center
RECRUITING

Billings, Montana, 59101, United States

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Bozeman Health Deaconess Hospital
RECRUITING

Bozeman, Montana, 59715, United States

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Camden Clark Medical Center
RECRUITING

Parkersburg, West Virginia, 26101, United States

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Cancer Centers of Southwest Oklahoma Research
RECRUITING

Lawton, Oklahoma, 73505, United States

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Carle Cancer Center
RECRUITING

Urbana, Illinois, 61801, United States

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Carle Physician Group-Effingham
RECRUITING

Effingham, Illinois, 62401, United States

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Carle Physician Group-Mattoon/Charleston
RECRUITING

Mattoon, Illinois, 61938, United States

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Carle at The Riverfront
RECRUITING

Danville, Illinois, 61832, United States

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Community Hospital of Anaconda
RECRUITING

Anaconda, Montana, 59711, United States

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Community Medical Center
RECRUITING

Missoula, Montana, 59804, United States

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Emory University Hospital Midtown
RECRUITING

Atlanta, Georgia, 30308, United States

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Good Samaritan Hospital - Cincinnati
RECRUITING

Cincinnati, Ohio, 45220, United States

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Heartland Oncology and Hematology LLP
SUSPENDED

Council Bluffs, Iowa, 51503, United States
Ingalls Memorial Hospital
RECRUITING

Harvey, Illinois, 60426, United States

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Iowa Methodist Medical Center
RECRUITING

Des Moines, Iowa, 50309, United States

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Keck Medicine of USC Koreatown
SUSPENDED

Los Angeles, California, 90020, United States
Kootenai Clinic Cancer Services - Post Falls
RECRUITING

Post Falls, Idaho, 83854, United States

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Kootenai Clinic Cancer Services - Sandpoint
RECRUITING

Sandpoint, Idaho, 83864, United States

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Kootenai Health - Coeur d'Alene
RECRUITING

Coeur d'Alene, Idaho, 83814, United States

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Logan Health Medical Center
RECRUITING

Kalispell, Montana, 59901, United States

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Los Angeles General Medical Center
RECRUITING

Los Angeles, California, 90033, United States

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Marshfield Medical Center - Minocqua
RECRUITING

Minocqua, Wisconsin, 54548, United States

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Marshfield Medical Center - Weston
RECRUITING

Weston, Wisconsin, 54476, United States

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Marshfield Medical Center-EC Cancer Center
RECRUITING

Eau Claire, Wisconsin, 54701, United States

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Marshfield Medical Center-Marshfield
RECRUITING

Marshfield, Wisconsin, 54449, United States

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Marshfield Medical Center-Rice Lake
RECRUITING

Rice Lake, Wisconsin, 54868, United States

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Marshfield Medical Center-River Region at Stevens Point
RECRUITING

Stevens Point, Wisconsin, 54482, United States

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Medical University of South Carolina
RECRUITING

Charleston, South Carolina, 29425, United States

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Memorial Sloan Kettering Basking Ridge
RECRUITING

Basking Ridge, New Jersey, 07920, United States

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Memorial Sloan Kettering Bergen
RECRUITING

Montvale, New Jersey, 07645, United States

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Memorial Sloan Kettering Cancer Center
RECRUITING

New York, New York, 10065, United States

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Memorial Sloan Kettering Commack
RECRUITING

Commack, New York, 11725, United States

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Memorial Sloan Kettering Monmouth
RECRUITING

Middletown, New Jersey, 07748, United States

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Memorial Sloan Kettering Nassau
RECRUITING

Uniondale, New York, 11553, United States

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Memorial Sloan Kettering Westchester
RECRUITING

Harrison, New York, 10604, United States

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Mercy Cancer Center-West Lakes
RECRUITING

Clive, Iowa, 50325, United States

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Mercy Hospital South
RECRUITING

St Louis, Missouri, 63128, United States

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Mercy Medical Center - Des Moines
RECRUITING

Des Moines, Iowa, 50314, United States

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Methodist Jennie Edmundson Hospital
RECRUITING

Council Bluffs, Iowa, 51503, United States

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Nebraska Cancer Specialists/Oncology Hematology West PC - MECC
RECRUITING

Omaha, Nebraska, 68114, United States

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Nebraska Cancer Specialists/Oncology Hematology West PC - MEJ
SUSPENDED

Council Bluffs, Iowa, 51503, United States
Nebraska Methodist Hospital
RECRUITING

Omaha, Nebraska, 68114, United States

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NorthShore University HealthSystem-Evanston Hospital
RECRUITING

Evanston, Illinois, 60201, United States

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NorthShore University HealthSystem-Glenbrook Hospital
RECRUITING

Glenview, Illinois, 60026, United States

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NorthShore University HealthSystem-Highland Park Hospital
RECRUITING

Highland Park, Illinois, 60035, United States

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Northwestern Medicine Cancer Center Delnor
RECRUITING

Geneva, Illinois, 60134, United States

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Northwestern Medicine Cancer Center Kishwaukee
RECRUITING

DeKalb, Illinois, 60115, United States

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Northwestern Medicine Cancer Center Warrenville
RECRUITING

Warrenville, Illinois, 60555, United States

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Northwestern Medicine Glenview Outpatient Center
RECRUITING

Glenview, Illinois, 60026, United States

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Northwestern Medicine Grayslake Outpatient Center
RECRUITING

Grayslake, Illinois, 60030, United States

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Northwestern Medicine Lake Forest Hospital
RECRUITING

Lake Forest, Illinois, 60045, United States

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Northwestern Medicine Orland Park
RECRUITING

Orland Park, Illinois, 60462, United States

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Northwestern University
RECRUITING

Chicago, Illinois, 60611, United States

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Novant Health Cancer Institute - Huntersville
RECRUITING

Huntersville, North Carolina, 28078, United States

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Novant Health Cancer Institute - Matthews
RECRUITING

Matthews, North Carolina, 28105, United States

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Novant Health Cancer Institute - Mooresville
RECRUITING

Mooresville, North Carolina, 28117, United States

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Novant Health Presbyterian Medical Center
RECRUITING

Charlotte, North Carolina, 28204, United States

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Oklahoma Cancer Specialists and Research Institute-Tulsa
SUSPENDED

Tulsa, Oklahoma, 74146, United States
Oncology Associates PC
SUSPENDED

Omaha, Nebraska, 68114, United States
Oregon Health and Science University
RECRUITING

Portland, Oregon, 97239, United States

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Saint Alphonsus Cancer Care Center-Boise
SUSPENDED

Boise, Idaho, 83706, United States
Saint Alphonsus Cancer Care Center-Caldwell
SUSPENDED

Caldwell, Idaho, 83605, United States
Saint Alphonsus Cancer Care Center-Nampa
SUSPENDED

Nampa, Idaho, 83687, United States
Saint Alphonsus Cancer Care Center-Ontario
SUSPENDED

Ontario, Oregon, 97914, United States
Sanford Bismarck Medical Center
RECRUITING

Bismarck, North Dakota, 58501, United States

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Sanford Broadway Medical Center
RECRUITING

Fargo, North Dakota, 58122, United States

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Sanford Cancer Center Oncology Clinic
RECRUITING

Sioux Falls, South Dakota, 57104, United States

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Sanford Joe Lueken Cancer Center
RECRUITING

Bemidji, Minnesota, 56601, United States

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Sanford Roger Maris Cancer Center
RECRUITING

Fargo, North Dakota, 58122, United States

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Sanford USD Medical Center - Sioux Falls
RECRUITING

Sioux Falls, South Dakota, 57117-5134, United States

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Stanford Cancer Institute Palo Alto
RECRUITING

Palo Alto, California, 94304, United States

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Tufts Medical Center
RECRUITING

Boston, Massachusetts, 02111, United States

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UC Comprehensive Cancer Center at Silver Cross
RECRUITING

New Lenox, Illinois, 60451, United States

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UC Irvine Health/Chao Family Comprehensive Cancer Center
RECRUITING

Orange, California, 92868, United States

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UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care
RECRUITING

Irvine, California, 92612, United States

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UI Health Care Mission Cancer and Blood - Ankeny Clinic
RECRUITING

Ankeny, Iowa, 50023, United States

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UI Health Care Mission Cancer and Blood - Des Moines Clinic
RECRUITING

Des Moines, Iowa, 50309, United States

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UI Health Care Mission Cancer and Blood - Laurel Clinic
RECRUITING

Des Moines, Iowa, 50314, United States

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UI Health Care Mission Cancer and Blood - Waukee Clinic
RECRUITING

Waukee, Iowa, 50263, United States

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UI Health Care Mission Cancer and Blood - West Des Moines Clinic
RECRUITING

Clive, Iowa, 50325, United States

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UNC Lineberger Comprehensive Cancer Center
RECRUITING

Chapel Hill, North Carolina, 27599, United States

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USC / Norris Comprehensive Cancer Center
RECRUITING

Los Angeles, California, 90033, United States

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USC Norris Oncology/Hematology-Newport Beach
RECRUITING

Newport Beach, California, 92663, United States

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University of Chicago Comprehensive Cancer Center
RECRUITING

Chicago, Illinois, 60637, United States

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University of Chicago Medicine-Orland Park
RECRUITING

Orland Park, Illinois, 60462, United States

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University of Illinois
RECRUITING

Chicago, Illinois, 60612, United States

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University of Oklahoma Health Sciences Center
RECRUITING

Oklahoma City, Oklahoma, 73104, United States

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VCU Massey Cancer Center at Stony Point
RECRUITING

Richmond, Virginia, 23235, United States

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VCU Massey Comprehensive Cancer Center
RECRUITING

Richmond, Virginia, 23298, United States

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Vanderbilt University/Ingram Cancer Center
RECRUITING

Nashville, Tennessee, 37232, United States

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West Virginia University Healthcare
RECRUITING

Morgantown, West Virginia, 26506, United States

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Conditions

Explore the condition pages connected to this study.

METASTATIC NASOPHARYNGEAL CARCINOMA RECURRENT NASOPHARYNGEAL CARCINOMA STAGE IV NASOPHARYNGEAL CARCINOMA AJCC V8