Tailored chemo doses aim to boost leukemia treatment in young adults
NCT ID NCT00136435
First seen Nov 01, 2025 · Last updated Apr 25, 2026 · Updated 19 times
Summary
This study tested whether giving personalized doses of the chemotherapy drug L-asparaginase could be safer and more effective for adults aged 18 to 50 with untreated acute lymphoblastic leukemia (ALL). Researchers used a pediatric-inspired treatment plan and adjusted doses based on how each patient's body processed the drug. The goal was to see if more patients could complete all 30 planned doses, which may improve long-term disease control.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02115, United States
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Hospital Maisonneuve-Rosemont
Montreal, Quebec, Canada
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London Health Sciences Centre
London, Ontario, Canada
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Manitoba Blood & Marrow Transplant Program CancerCare Manitoba
Winnipeg, Manitoba, Canada
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Massachusetts General Hospital
Boston, Massachusetts, 02115, United States
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McMaster University Medical Center
Hamilton, Ontario, Canada
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Queen Elizabeth II
Halifax, Canada
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Queen's University
Kingston, Ontario, Canada
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Royal Victoria Hospital
Montreal, Quebec, Canada
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Saskatoon Cancer Centre
Saskatoon, Saskatchewan, Canada
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Sunnybrook Health Sciences Centre
Toronto, Ontario, Canada
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University Of Columbia Medical Center
New York, New York, United States
Conditions
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