Stem cells could offer new hope for severe eczema sufferers

NCT ID NCT04137562

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This Phase 2 trial tests whether a stem cell therapy called ADSTEM can safely and effectively treat moderate-to-severe atopic dermatitis (eczema). About 118 adults with long-lasting eczema that hasn't responded well to standard creams will receive either ADSTEM stem cells or a placebo via IV infusion. Researchers will track how many patients see at least a 50% improvement in their eczema symptoms over 16 weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ADSTEM stem cells (mesenchymal stem cells) given by IV infusion

What this could lead to

If it works, this could lead to a new treatment option that helps control moderate-to-severe atopic dermatitis with fewer side effects than current therapies.

What could go wrong

This is an early Phase 2 trial with only 118 people, so results may not apply to everyone. The treatment is still experimental, and its long-term safety and effectiveness are not yet proven.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

atopic eczema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Chung-Ang University Hospital

    Seoul, Seoulteukbyeolsi, South Korea

  • Chungnam National University Hospital

    Daejeon, Chungcheongnam-do, South Korea

  • Korea University AnSan Hospital

    Ansan, Gyeonggi-do, South Korea

  • Kyunghee University Medical Center

    Seoul, Seoulteukbyeolsi, South Korea

  • SMG-SNU Boramae Medical Center

    Seoul, Seoulteukbyeolsi, South Korea

  • Seoul National University Hospital

    Seoul, Seoulteukbyeolsi, South Korea