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New drug trial aims to slow kidney damage in genetic disease

NCT ID NCT06902558

Recruiting now Disease control Sponsor: AbbVie Source: ClinicalTrials.gov ↗

Summary

This study is testing whether an investigational drug called ABBV-CLS-628 can safely slow the progression of autosomal dominant polycystic kidney disease (ADPKD), a genetic condition where fluid-filled cysts damage the kidneys. About 240 adults with ADPKD will receive either the drug or a placebo via intravenous infusion every four weeks for nearly two years. Researchers will measure changes in kidney size and function to see if the treatment helps control the disease.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • 2CA-Braga, Hospital de Braga /ID# 271258

    RECRUITING

    Braga, 4710-243, Portugal

  • Academic Medical Research Institute - Los Angeles /ID# 270502

    RECRUITING

    Los Angeles, California, 90022, United States

  • Albert Schweitzer Ziekenhuis, locatie Dordwijk /ID# 271247

    RECRUITING

    Dordrecht, South Holland, 3318 AT, Netherlands

  • Arlington Nephrology /ID# 270494

    RECRUITING

    Arlington, Texas, 76015, United States

  • Azienda Ospedaliero-Universitaria Policlinico Umberto I /ID# 271563

    RECRUITING

    Rome, Roma, 00161, Italy

  • Beth Israel Deaconess Medical Center /ID# 271408

    RECRUITING

    Boston, Massachusetts, 02215, United States

  • Brookview Hills Research Associates /ID# 271449

    RECRUITING

    Winston-Salem, North Carolina, 27103, United States

  • CARE Institute - Idaho Falls /ID# 272005

    RECRUITING

    Idaho Falls, Idaho, 83404, United States

  • CARE-Boise Kidney /ID# 270628

    RECRUITING

    Boise, Idaho, 83706, United States

  • CHU Brest - Hôpital de la Cavale Blanche /ID# 271114

    RECRUITING

    Brest, Brittany Region, 29200, France

  • CHU Toulouse - Hôpital Rangueil /ID# 271138

    RECRUITING

    Toulouse, Occitanie, 31400, France

  • CHU de Liege /ID# 270631

    RECRUITING

    Liège, 4000, Belgium

  • Charite Universitaetsmedizin Berlin - Campus Mitte /ID# 270935

    RECRUITING

    Berlin, 10117, Germany

  • Cliniques Universitaires UCL Saint-Luc /ID# 270635

    RECRUITING

    Brussels, Brussels Capital, 1200, Belgium

  • Emory University School Of Medicine - Atlanta /ID# 271947

    RECRUITING

    Atlanta, Georgia, 30322, United States

  • Fiona Stanley Hospital /ID# 271173

    RECRUITING

    Murdoch, Western Australia, 6150, Australia

  • Fundacio Puigvert /ID# 270491

    RECRUITING

    Barcelona, 08025, Spain

  • Hallym University Kangnam Sacred Heart Hospital /ID# 271329

    RECRUITING

    Seoul, Seoul Teugbyeolsi, 07441, South Korea

  • Hokkaido University Hospital /ID# 271385

    RECRUITING

    Sapporo, Hokkaido, 060-8648, Japan

  • Hopital Edouard Herriot /ID# 271142

    RECRUITING

    Lyon, Auvergne-Rhône-Alpes, 69003, France

  • Hopital Universitaire Necker Enfants Malades /ID# 271146

    RECRUITING

    Paris, Île-de-France Region, 75015, France

  • Hopital de la Conception /ID# 271152

    RECRUITING

    Marseille, Provence-Alpes-Côte d'Azur Region, 13005, France

  • Horizon Research Group - Coral Gables /ID# 270857

    RECRUITING

    Coral Gables, Florida, 33134, United States

  • Hospital Clínico Universitario de Valencia /ID# 270837

    RECRUITING

    Valencia, 46010, Spain

  • Hospital Universitari de Bellvitge /ID# 270489

    RECRUITING

    L'Hospitalet de Llobregat, Barcelona, 08907, Spain

    Contact Phone: •••-•••-••••

  • Hospital Universitario 12 de Octubre /ID# 270829

    RECRUITING

    Madrid, 28041, Spain

    Contact Phone: •••-•••-••••

  • Hospital Universitario Fundacion Jimenez Diaz /ID# 270485

    RECRUITING

    Madrid, 28040, Spain

  • Hospital Universitario Virgen de las Nieves /ID# 270918

    RECRUITING

    Granada, 18014, Spain

  • Icahn School of Medicine at Mount Sinai /ID# 271440

    RECRUITING

    New York, New York, 10029, United States

  • Infigo Clinical Research /ID# 270844

    RECRUITING

    Sanford, Florida, 32771, United States

  • Juntendo University Hospital /ID# 271722

    RECRUITING

    Bunkyo-ku, Tokyo, 113-8431, Japan

  • Keimyung University Dongsan Hospital /ID# 272455

    RECRUITING

    Daegu, Gyeongsangbuk-do, 42601, South Korea

  • Knoxville Kidney Center /ID# 270706

    RECRUITING

    Knoxville, Tennessee, 37923, United States

  • Lumc /Id# 271844

    RECRUITING

    Leiden, South Holland, 2333 ZA, Netherlands

  • Mayo Clinic Hospital Jacksonville /ID# 271011

    RECRUITING

    Jacksonville, Florida, 32224, United States

  • Mayo Clinic Hospital Rochester /ID# 270428

    RECRUITING

    Rochester, Minnesota, 55905, United States

  • Medizinische Hochschule Hannover /ID# 270938

    RECRUITING

    Hanover, Lower Saxony, 30625, Germany

  • National Hospital Org Chiba Medical Center Chibahigashi National Hospital /ID# 272022

    RECRUITING

    Chiba, 260-8712, Japan

  • National Hospital Organization Kyoto Medical Center /ID# 271782

    RECRUITING

    Kyoto, Kyoto, 612-8555, Japan

  • National Institute of Clinical Research - Garden Grove /ID# 271418

    RECRUITING

    Garden Grove, California, 92844, United States

    Contact Phone: •••-•••-••••

  • Nature Coast Clinical Research - Inverness /ID# 270875

    RECRUITING

    Inverness, Florida, 34452-4717, United States

  • Nephrology Associates - Chattanooga - East Third Street /ID# 270701

    RECRUITING

    Chattanooga, Tennessee, 37404, United States

  • Northeast Clinical Research Center /ID# 270838

    RECRUITING

    Bethlehem, Pennsylvania, 18017, United States

  • Northwestern University Feinberg School of Medicine /ID# 271409

    RECRUITING

    Chicago, Illinois, 60611-2927, United States

  • Panax Clinical Research /ID# 270851

    RECRUITING

    Miami, Florida, 33014, United States

  • Pusan National University Hospital /ID# 271429

    RECRUITING

    Busan, Busan Gwang Yeogsi, 49241, South Korea

  • Renal Disease Research Institute /ID# 270339

    RECRUITING

    Fort Worth, Texas, 76104, United States

  • Royal Adelaide Hospital /ID# 273114

    RECRUITING

    Adelaide, South Australia, 5000, Australia

  • Royal Brisbane and Women's Hospital /ID# 271224

    RECRUITING

    Brisbane, Queensland, 4029, Australia

  • SMG-SNU Boramae Medical Center /ID# 271227

    RECRUITING

    Seoul, Seoul Teugbyeolsi, 07061, South Korea

  • Seoul National University Hospital /ID# 271331

    RECRUITING

    Seoul, Seoul Teugbyeolsi, 03080, South Korea

  • South Florida Research Institute /ID# 270848

    RECRUITING

    Fort Lauderdale, Florida, 33313, United States

  • St. Clair Nephrology /ID# 271445

    RECRUITING

    Shelby, Michigan, 48315, United States

  • Swedish Medical Center - Seattle /ID# 270344

    RECRUITING

    Seattle, Washington, 98104, United States

  • TUM Klinikum rechts der Isar /ID# 271522

    RECRUITING

    Munich, Bavaria, 81675, Germany

  • Tufts Medical Center /ID# 270323

    RECRUITING

    Boston, Massachusetts, 02111-1552, United States

  • UC Irvine Medical Center /ID# 270811

    RECRUITING

    Orange, California, 92868-3201, United States

  • UZ Leuven /ID# 270638

    RECRUITING

    Leuven, Vlaams-Brabant, 3000, Belgium

  • Unidade Local de Saude de Almada-Seixal, EPE /ID# 271257

    RECRUITING

    Almada, Setúbal District, 2805-267, Portugal

  • Unidade Local de Saude de Lisboa Ocidental, EPE /ID# 271261

    RECRUITING

    Lisbon, 1449-005, Portugal

  • Unidade Local de Saude de Sao Jose, EPE /ID# 271255

    RECRUITING

    Lisbon, 1150-199, Portugal

  • Unidade Local de Saude do Algarve, EPE /ID# 271819

    RECRUITING

    Faro, 8000-386, Portugal

  • Universitaetsklinikum Koeln /ID# 270937

    RECRUITING

    Cologne, North Rhine-Westphalia, 50937, Germany

  • Universitair Medisch Centrum Groningen /ID# 271249

    RECRUITING

    Groningen, 9713 GR, Netherlands

  • University Of California, San Francisco /ID# 270326

    RECRUITING

    San Francisco, California, 94143-2202, United States

  • University Of Michigan /ID# 270436

    RECRUITING

    Ann Arbor, Michigan, 48109-5000, United States

  • University of Iowa /ID# 270492

    RECRUITING

    Iowa City, Iowa, 52242, United States

  • University of Kansas Medical Center /ID# 271946

    RECRUITING

    Kansas City, Kansas, 66160, United States

  • University of North Carolina at Chapel Hill /ID# 274800

    RECRUITING

    Chapel Hill, North Carolina, 27599-0001, United States

  • University of Pennsylvania /ID# 270301

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

  • University of Virginia /ID# 270329

    RECRUITING

    Charlottesville, Virginia, 22908, United States

  • Valiance Clinical Research - Huntington Park /ID# 270634

    RECRUITING

    Huntington Park, California, 90255, United States

  • Washington University /ID# 271436

    RECRUITING

    St Louis, Missouri, 63110, United States

  • Westmead Hospital /ID# 271156

    RECRUITING

    Westmead, New South Wales, 2145, Australia

  • Yale University School of Medicine /ID# 270675

    RECRUITING

    New Haven, Connecticut, 06510, United States

Conditions

Explore the condition pages connected to this study.

AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE