Researchers trace a common genetic root for kidney disease in italian families

NCT ID NCT06594367

Summary

This was an observational study that aimed to understand if a specific genetic change (a deletion in the PKD2 gene) found in 10 patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD) came from a common ancestor in the Bergamo province of Italy. Researchers analyzed the DNA of these patients and their family histories to see how this specific genetic change was linked to the different ways the disease appeared, from mild to more severe cases. The goal was to improve genetic diagnosis and counseling for affected families.

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Contacts and locations

Locations

  • Clinical Research Centre for Rare Diseases Aldo e Cele Daccò

    Ranica, BG, 24020, Italy

Conditions

Explore the condition pages connected to this study.