Gene test may tailor Post-Surgery pain relief

NCT ID NCT05966129

First seen Mar 22, 2026 · Last updated Jun 13, 2026 · Updated 9 times

Summary

This study looked at whether testing people's genes before surgery can help doctors choose better pain medicines. Over 1,600 participants were randomly assigned to either get genetic testing right away or wait six months. The goal was to see if knowing how someone processes pain drugs leads to better pain control and less opioid use.

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Contacts and locations

Locations

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

  • Icahn School of Medicine at Mount Sinai

    New York, New York, 10029, United States

  • Indiana University

    Indianapolis, Indiana, 46202, United States

  • Meharry Medical College

    Nashville, Tennessee, 37208, United States

  • Nashville General Hospital

    Nashville, Tennessee, 37208, United States

  • Nemours Children's Health System

    Wilmington, Delaware, 19803, United States

  • Nemours Children's Health System

    Jacksonville, Florida, 32207, United States

  • Nemours Children's Health System

    Orlando, Florida, 32827, United States

  • Sanford Health

    Fargo, North Dakota, 58104, United States

  • University of Florida - Gainesville

    Gainesville, Florida, 32610, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232, United States

Conditions

Explore the condition pages connected to this study.