Which ADHD drug works best for preschoolers? new study aims to find out

NCT ID NCT07300956

First seen Jan 07, 2026 · Last updated May 05, 2026 · Updated 17 times

Summary

This study compares two common ADHD medications—Methylphenidate and Guanfacine—in children aged 3 to 5 years. The goal is to see which one improves symptoms more and is better tolerated. About 370 children will take part, and their progress will be tracked over 16 weeks.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Boston Children's Hospital

    Boston, Massachusetts, 02115, United States

    Contact

    Contact Email: •••••@•••••

  • Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

    Contact Email: •••••@•••••

    Contact

  • Children's Mercy Hospital

    Kansas City, Missouri, 64108, United States

    Contact Email: •••••@•••••

    Contact

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

    Contact Email: •••••@•••••

    Contact

  • Stanford Medicine Children's Health

    Palo Alto, California, 94304, United States

    Contact

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.