New cocktail of drugs shows promise for stomach cancer in early trial

NCT ID NCT07110571

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 2 study is testing several new drug combinations for people with stomach or gastroesophageal junction cancer who have not had prior treatment. The combinations include an immunotherapy drug (adebrelimab) plus targeted drugs (SHR-A1811, SHR-A1904, or SHR-8068) and chemotherapy. The goal is to see if these combinations can shrink or eliminate tumors, while monitoring safety. About 200 participants will be enrolled across multiple centers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

adebrelimab (an immunotherapy drug) combined with SHR-A1811, SHR-A1904, or SHR-8068 (targeted drugs) and chemotherapy

What this could lead to

If successful, this could point toward more effective combination treatments for gastric or gastroesophageal junction cancer.

What could go wrong

This is an early Phase 2 trial with only 200 participants, so results may not apply to all patients. Combination therapies also carry higher risk of side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

gastric adenocarcinoma gastric cancer gastric neoplasm gastroesophageal cancer gastroesophageal junction adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Fourth Hospital of Hebei Medical University

    RECRUITING

    Shijiazhuang, Hebei, 050010, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Zhejiang Cancer Hospital

    RECRUITING

    Hangzhou, Zhejiang, 310022, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact