New drug combo aims to shrink Hard-to-Treat thymic tumors before surgery

NCT ID NCT07479628

First seen Mar 20, 2026 · Last updated May 15, 2026 · Updated 8 times

Summary

This phase II trial tests whether adding the immunotherapy drug adebrelimab to standard chemotherapy and radiation before surgery can shrink tumors in people with locally advanced thymic carcinoma. About 31 participants will receive 2-4 cycles of this combination, then have surgery if the tumor shrinks enough. After surgery, they will continue adebrelimab for up to one year to help prevent the cancer from coming back.

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