Lung cancer combo therapy aims to clear tumors before surgery

NCT ID NCT07704645

First seen Jul 15, 2026 · Last updated Jul 16, 2026 · Updated 1 time

Summary

This phase II trial investigates whether combining the immunotherapy adebelizumab with other anti-tumor drugs, given before and after surgery, can improve outcomes for people with resectable non-small cell lung cancer. The study enrolls adults aged 18-70 with stage II or IIIA disease who are candidates for curative surgery. The main goal is to see if the treatment leads to a complete disappearance of cancer cells in the removed tissue (pathological complete response).

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
adebelizumab combined with other anti-tumor drugs
What this could lead to
If successful, this combination approach could improve the chances of eliminating all cancer before surgery and reduce the risk of recurrence in people with early-stage lung cancer.
What could go wrong
This is a phase II trial, so the combination's safety and effectiveness are not yet proven. Side effects from the drug combination could be significant, and the results may not lead to a new standard treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Shanghai Pulmonary Hospital

    Shanghai, Shanghai Municipality, 200000, China

    Contact

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